CD137 抗体 (AA 24-186)
Quick Overview for CD137 抗体 (AA 24-186) (ABIN5611112)
抗原
See all CD137 (TNFRSF9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 24-186
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原理
- CD137 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD137 (AA: 24-186) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
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别名
- CD137
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背景
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
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分子量
- 27.9 kDa
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UniProt
- Q07011
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途径
- Cancer Immune Checkpoints
抗原
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