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BLM 抗体 (Internal Region, pThr99)

BLM 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5596805
发货至: 中国
  • 抗原 See all BLM 抗体
    BLM (Bloom Syndrome RecQ Like Helicase (BLM))
    抗原表位
    • 15
    • 11
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region, pThr99
    适用
    • 55
    • 9
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 3
    • 3
    克隆类型
    • 58
    • 2
    多克隆
    标记
    • 33
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BLM antibody is un-conjugated
    应用范围
    • 48
    • 32
    • 13
    • 13
    • 13
    • 12
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应 (详细)
    A BLAST analysis was used to suggest cross-reactivity with human based on 100% sequence homology. Cross-reactivity with BLM pT99 from other sources has not been determined.
    纯化方法
    Anti-BLM pT99 was affinity purified from monospecific antiserum by immunoaffinity chromatography.
    免疫原

    Immunogen: Anti-BLM pT99 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human Bloom syndrome protein.

    Immunogen Type: Peptide

    亚型
    IgG
    Top Product
    Discover our top product BLM Primary Antibody
  • 应用备注

    Application Note: Anti-BLM pT99 antibody is useful for ELISA, Immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~159 kDa corresponding to the appropriate cell lysate or extract.

    Western Blot Dilution: 1 μg/mL

    ELISA Dilution: 1: 10,000

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.11 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    BLM (Bloom Syndrome RecQ Like Helicase (BLM))
    别名
    BLM (BLM 产品)
    别名
    BS antibody, RECQ2 antibody, RECQL2 antibody, RECQL3 antibody, blm-A antibody, xBLM antibody, ORF1 antibody, Bloom syndrome RecQ like helicase antibody, Bloom syndrome RecQ like helicase S homeolog antibody, Bloom syndrome, RecQ like helicase antibody, BLM antibody, blm.S antibody, Blm antibody
    背景

    Synonyms: DNA helicase, RecQ-like type 2, RECQ2, RECQL3, Bloom syndrome protein

    Background: BLM pT99 product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes. Anti-BLM pT99 antibody is ideal for researchers interested in Epigenetics and Nuclear Signaling or DNA Damage & Repair research.

    Gene Name: BLM

    途径
    DNA Damage Repair
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