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BLM 抗体 (pThr99)

BLM 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138888
发货至: 中国
  • 抗原 See all BLM 抗体
    BLM (Bloom Syndrome RecQ Like Helicase (BLM))
    抗原表位
    • 15
    • 11
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr99
    适用
    • 55
    • 9
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 3
    • 3
    克隆类型
    • 58
    • 2
    多克隆
    标记
    • 33
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BLM antibody is un-conjugated
    应用范围
    • 48
    • 32
    • 13
    • 13
    • 13
    • 12
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of threonine 99 (Q-E-T(p)-Q-R) derived from Human Bloom Syndrome.
    亚型
    IgG
    Top Product
    Discover our top product BLM Primary Antibody
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BLM (Bloom Syndrome RecQ Like Helicase (BLM))
    别名
    BLM (BLM 产品)
    别名
    BS antibody, RECQ2 antibody, RECQL2 antibody, RECQL3 antibody, blm-A antibody, xBLM antibody, ORF1 antibody, Bloom syndrome RecQ like helicase antibody, Bloom syndrome RecQ like helicase S homeolog antibody, Bloom syndrome, RecQ like helicase antibody, BLM antibody, blm.S antibody, Blm antibody
    背景

    Background:

    Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).

    Ellis N.A., Cell 83:655-666(1995).
    Karow J.K., J. Biol. Chem. 272:30611-30614(1997).
    Pichierri P., EMBO J. 23:3154-3163(2004).

    Aliases: Blm antibody, BLM_HUMAN antibody, Bloom syndrome antibody, Bloom syndrome protein antibody, Bloom syndrome RecQ helicase like antibody, BS antibody, DNA helicase antibody, DNA helicase RecQ like type 2 antibody, MGC126616 antibody, MGC131618 antibody, MGC131620 antibody, RECQ 2 antibody, RECQ like antibody, RecQ like type 2 antibody, RecQ protein like 3 antibody, RecQ protein-like 3 antibody, RecQ-like type 2 antibody, RecQ2 antibody, RECQL 2 antibody, RECQL 3 antibody, RECQL2 antibody, RECQL3 antibody, type 2 antibody

    UniProt
    P54132
    途径
    DNA Damage Repair
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