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HLA-DPB1 抗体

HLA-DPB1 适用: 人 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal Bra-14 unconjugated
产品编号 ABIN5579986
发货至: 中国
  • 抗原 See all HLA-DPB1 抗体
    HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
    适用
    • 63
    • 21
    • 3
    • 2
    • 2
    宿主
    • 51
    • 12
    小鼠
    克隆类型
    • 46
    • 17
    单克隆
    标记
    • 34
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    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This HLA-DPB1 antibody is un-conjugated
    应用范围
    • 49
    • 27
    • 27
    • 22
    • 15
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 2
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse monoclonal antibody raised against native human HLA-DP/HLA-DR.
    特异性
    Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP and HLA-DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DP, DQ and DR, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
    交叉反应
    免疫原
    Human REH cells.
    克隆位点
    Bra-14
    亚型
    IgG3
    Top Product
    Discover our top product HLA-DPB1 Primary Antibody
  • 应用备注
    Flow Cytometry (0.5-1 μg/106 cells in 0.1 mL)
    Immunofluorescence (0.5-1 μg/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 μg/mL)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 10 mM PBS (0.05 % BSA, 0.05 % sodium azide).
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 4°C.
  • 抗原
    HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
    别名
    HLA-DPB1 (HLA-DPB1 产品)
    别名
    PATR-DPB1 antibody, B-LB antibody, B-LB2 antibody, B-LB21 antibody, BLB1 antibody, GSP-BLB1 antibody, DPB1 antibody, HLA-DP antibody, HLA-DP1B antibody, HLA-DPB antibody, major histocompatibility complex, class II, DP beta 1 antibody, Major histocompatibility complex class II beta chain BLB1 antibody, PATR-DPB1 antibody, BLB1 antibody, HLA-DPB1 antibody
    背景
    Full Gene Name: major histocompatibility complex, class II, DP beta 1
    Synonyms: DPB1,HLA-DP1B
    基因ID
    3115, 3122
    途径
    TCR Signaling, Cancer Immune Checkpoints
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