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HLA-DPB1 抗体

HLA-DPB1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7256818
发货至: 中国
  • 抗原 See all HLA-DPB1 抗体
    HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
    适用
    • 63
    • 20
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 50
    • 13
    克隆类型
    • 45
    • 18
    多克隆
    标记
    • 34
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-DPB1 antibody is un-conjugated
    应用范围
    • 49
    • 28
    • 27
    • 21
    • 16
    • 13
    • 13
    • 11
    • 4
    • 4
    • 3
    • 2
    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human HLA-DPB1 (NP_002112.3).
    亚型
    IgG
    Top Product
    Discover our top product HLA-DPB1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
    别名
    HLA-DPB1 (HLA-DPB1 产品)
    别名
    PATR-DPB1 antibody, B-LB antibody, B-LB2 antibody, B-LB21 antibody, BLB1 antibody, GSP-BLB1 antibody, DPB1 antibody, HLA-DP antibody, HLA-DP1B antibody, HLA-DPB antibody, major histocompatibility complex, class II, DP beta 1 antibody, Major histocompatibility complex class II beta chain BLB1 antibody, PATR-DPB1 antibody, BLB1 antibody, HLA-DPB1 antibody
    背景
    HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
    基因ID
    3115
    UniProt
    P04440
    途径
    TCR Signaling, Cancer Immune Checkpoints
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