MCM2 抗体
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北京 101111
Quick Overview for MCM2 抗体 (ABIN5542011)
抗原
See all MCM2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects ~120 kDa of MCM2 protein from whole cell lysate of human cell lines.
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交叉反应 （详细）
- Does not react with Mouse (WR19L) and Rat (Rat1).
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纯化方法
- Protein A agarose
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免疫原
- Recombinant human MCM2 protein corresponding to full-length amino acids
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亚型
- IgG1
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anti-Minichromosome Maintenance Complex Component 2 (MCM2) antibody
MCM2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2B3 unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) antibodyMCM2 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) antibodyMCM2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 805-904) antibodyMCM2 适用: 人 WB, IF, ELISA, IP 宿主: 小鼠 Monoclonal 6A8 unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 884-904) antibodyMCM2 适用: 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 360-700) antibodyMCM2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (N-Term) antibodyMCM2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 889-904), (C-Term) antibodyMCM2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 649-677) antibodyMCM2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 2 (MCM2) (AA 601-700) antibodyMCM2 适用: 人, 小鼠 ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot: 1 μg/mL for chemiluminescence detection system. Immunocytochemistry: 5-10 μg/mL.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
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- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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别名
- mcm2
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背景
- In human cells, MCM4, - 6, and - 7 proteins form a stable complex, and MCM2 is loosely associated with this complex. The heterotrimeric MCM complex containing MCM4, - 6 and - 7 ha s DNA helicase activity, and such activity can be inhibited by the presence of MCM2. Cdc7/Dbf4 protein kinase, which is required for the initiation of DNA replication phosphorylates MCM2 in vitro and in vivo. From these observations, it's thought that phos phorylation of MCM2 may remove MCM2 from the MCM4, - 6, and - 7 complex to activate its DNA helicase activity at the onset of DNA replication.
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UniProt
- P49736
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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