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BMPR2 抗体 (N-Term)

BMPR2 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5535544
发货至: 中国
  • 抗原 See all BMPR2 抗体
    BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
    抗原表位
    • 15
    • 10
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-59, N-Term
    适用
    • 60
    • 42
    • 16
    • 3
    • 1
    人, 小鼠
    宿主
    • 54
    • 6
    • 1
    克隆类型
    • 55
    • 6
    多克隆
    标记
    • 33
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMPR2 antibody is un-conjugated
    应用范围
    • 48
    • 26
    • 18
    • 14
    • 13
    • 13
    • 9
    • 9
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    免疫原
    This BMPR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human BMPR2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product BMPR2 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    For FACS starting dilution is: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
    别名
    BMPR2 (BMPR2 产品)
    别名
    BMPR-II antibody, BMPR3 antibody, BMR2 antibody, BRK-3 antibody, PPH1 antibody, T-ALK antibody, 2610024H22Rik antibody, AL117858 antibody, AW546137 antibody, BB189135 antibody, BMP-2 antibody, BMPR-2 antibody, BMPRII antibody, Gm20272 antibody, Bmpr-II antibody, bmprii antibody, bone morphogenetic protein receptor type 2 antibody, bone morphogenetic protein receptor, type II b (serine/threonine kinase) antibody, bone morphogenetic protein receptor, type II (serine/threonine kinase) antibody, BMPR2 antibody, bmpr2b antibody, Bmpr2 antibody
    背景
    BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.
    分子量
    115 kDa
    基因ID
    659
    UniProt
    Q13873
    途径
    Growth Factor Binding
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