BMPR2 抗体 (N-Term)
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Quick Overview for BMPR2 抗体 (N-Term) (ABIN388741)
抗原
See all BMPR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 28-59, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This BMPR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from the N-terminal region of human BMPR2.
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亚型
- Ig Fraction
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anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) antibody
BMPR2 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) antibodyBMPR2 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1F12 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 28-59) antibodyBMPR2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-150) antibodyBMPR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-150) antibodyBMPR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-150) antibodyBMPR2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-56), (N-Term) antibodyBMPR2 适用: 人 FACS, IHC (p) 宿主: 兔 Polyclonal RB1806 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (Internal Region) antibodyBMPR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (C-Term) antibodyKO Validated BMPR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-56) antibodyBMPR2 适用: 人, 小鼠 ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
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有效期
- 6 months
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: "Correlating the Effects of Bone Morphogenic Protein to Secreted Soluble Factors from Fibroblasts and Mesenchymal Stem Cells in Regulating Regenerative Processes In Vitro." in: Tissue engineering. Part A, (2014) (PubMed).
: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." in: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).
: "Roles of miR-1-1 and miR-181c in ventricular septal defects." in: International journal of cardiology, Vol. 168, Issue 2, pp. 1441-6, (2013) (PubMed).
: "Binding of carbon nanotube to BMP receptor 2 enhances cell differentiation and inhibits apoptosis via regulating bHLH transcription factors." in: Cell death & disease, Vol. 3, pp. e308, (2012) (PubMed).
: "Expression of gremlin, a bone morphogenetic protein antagonist,is associated with vascular calcification in uraemia." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 24, Issue 4, pp. 1121-9, (2009) (PubMed).
: "Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 6, pp. L1526-42, (2007) (PubMed).
: "The BMP type II receptor is located in lipid rafts, including caveolae, of pulmonary endothelium in vivo and in vitro." in: Vascular pharmacology, Vol. 44, Issue 1, pp. 50-9, (2005) (PubMed).
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: "Correlating the Effects of Bone Morphogenic Protein to Secreted Soluble Factors from Fibroblasts and Mesenchymal Stem Cells in Regulating Regenerative Processes In Vitro." in: Tissue engineering. Part A, (2014) (PubMed).
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- BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
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别名
- BMPR2
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背景
- BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.
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分子量
- 115201
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基因ID
- 659
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NCBI登录号
- NP_001195
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UniProt
- Q13873
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途径
- Growth Factor Binding
抗原
-
