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TNNT3 抗体 (C-Term)

TNNT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5531203
发货至: 中国
  • 抗原 See all TNNT3 抗体
    TNNT3 (Fast Skeletal Troponin T (TNNT3))
    抗原表位
    • 12
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 217-245, C-Term
    适用
    • 41
    • 10
    • 9
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 29
    • 10
    • 2
    克隆类型
    • 33
    • 8
    多克隆
    标记
    • 23
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNNT3 antibody is un-conjugated
    应用范围
    • 32
    • 17
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TNNT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 amino acids from the C-terminal region of human TNNT3.
    亚型
    Ig Fraction
    Top Product
    Discover our top product TNNT3 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TNNT3 (Fast Skeletal Troponin T (TNNT3))
    别名
    TNNT3 (TNNT3 产品)
    别名
    fTnT antibody, tnnt3a antibody, TNTF antibody, TnTf antibody, Tnt antibody, Tnnt3 antibody, troponin T3, fast skeletal type antibody, troponin T3, skeletal, fast antibody, troponin T3, fast skeletal type S homeolog antibody, troponin T type 3 (skeletal, fast) antibody, troponin T1, slow skeletal type antibody, TNNT3 antibody, Tnnt3 antibody, tnnt3.S antibody, TNNT1 antibody
    背景
    The binding of Ca(2+) to the trimeric troponin complex initiates the process of muscle contraction. Increased Ca(2+) concentrations produce a conformational change in the troponin complex that is transmitted to tropomyosin dimers situated along actin filaments. The altered conformation permits increased interaction between a myosin head and an actin filament which, ultimately, produces a muscle contraction. The troponin complex has protein subunits C, I, and T. Subunit C binds Ca(2+) and subunit I binds to actin and inhibits actin-myosin interaction. Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca(2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that encode tissue-specific isoforms of subunit T for fast skeletal-, slow skeletal-, and cardiac-muscle. This gene encodes fast skeletal troponin T protein, also known as troponin T type 3. Alternative splicing results in multiple transcript variants encoding additional distinct troponin T type 3 isoforms. A developmentally regulated switch between fetal/neonatal and adult troponin T type 3 isoforms occurs. Additional splice variants have been described but their biological validity has not been established. Mutations in this gene may cause distal arthrogryposis multiplex congenita type 2B (DA2B).
    分子量
    32 kDa
    基因ID
    7140
    UniProt
    P45378
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