电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TNNT3 抗体

(Fast Skeletal Troponin T (TNNT3))
The binding of Ca(2+) to the trimeric troponin complex initiates the process of muscle contraction. Increased Ca(2+) concentrations produce a conformational change in the troponin complex that is transmitted to tropomyosin dimers situated along actin filaments. The altered conformation permits increased interaction between a myosin head and an actin filament which, ultimately, produces a muscle contraction. The troponin complex has protein subunits C, I, and T. Subunit C binds Ca(2+) and subunit I binds to actin and inhibits actin-myosin interaction. Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca(2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that encode tissue-specific isoforms of subunit T for fast skeletal-, slow skeletal-, and cardiac-muscle. This gene encodes fast skeletal troponin T protein\; also known as troponin T type 3. Alternative splicing results in multiple transcript variants encoding additional distinct troponin T type 3 isoforms. A developmentally regulated switch between fetal/neonatal and adult troponin T type 3 isoforms occurs. Additional splice variants have been described but their biological validity has not been established. Mutations in this gene may cause distal arthrogryposis multiplex congenita type 2B (DA2B). [provided by RefSeq, Oct 2009].
TNNT3 抗体  (AA 161-258) TNNT3 抗体  (AA 161-258) TNNT3 抗体 (AA 161-258) (ABIN563217)

TNNT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F12 unconjugated

TNNT3 抗体  (C-Term) TNNT3 抗体  (C-Term) TNNT3 抗体 (C-Term) (ABIN6257189)

TNNT3 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

TNNT3 抗体 TNNT3 抗体 TNNT3 抗体 (ABIN462336)

TNNT3 适用: 人, 小鸡, Quail WB, ELISA, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal T1-61 unconjugated

TNNT3 抗体 by Grade

Find TNNT3 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TNNT3 抗体 by 适用

Find TNNT3 抗体 for a variety of species such as anti-Human TNNT3, anti-Mouse TNNT3, anti-Rat TNNT3. The species listed below are among those available. Click on a link to go to the corresponding products.

TNNT3 抗体 by 应用范围

Find TNNT3 抗体 validated for a specific application such as WB, ELISA, IHC, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TNNT3 抗体 by 抗体来源

Find TNNT3 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

TNNT3 抗体 by 抗原表位

Find TNNT3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TNNT3 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TNNT3 抗体. Click on a link to go to the corresponding products.

TNNT3 抗体 by 克隆

Find TNNT3 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

TNNT3 抗体 by 标记

Find TNNT3 抗体 with a specific conjugate such as Biotin, APC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TNNT3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN563217
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, ICC, IF
Validations
  • (2)
Cat. No. ABIN6257189
Quantity 100 μL
Datasheet Datasheet
Reactivity Chicken, Human, Quail
Application WB, ELISA, IHC, IHC (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN462336
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN521034
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN521032
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN948581
Quantity 50 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN321848
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN5539524
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN1590029
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6738755
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7267145
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN2784496
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (2)
  • (1)
Cat. No. ABIN2784497
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF/ICC
Validations
  • (2)
Cat. No. ABIN2903982
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN6389411
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our TNNT3 抗体

Zhang, Pereyra, Wang, Birbrair, Reisz, Files, Purcell, Feng, Messi, Feng, Chalovich, Jin, Furdui, Delbono: "Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice." in: Aging cell, Vol. 15, Issue 3, pp. 488-98, (2016) (PubMed).

Zhang, Birbrair, Wang, Taylor, Messi, Delbono: "Troponin T nuclear localization and its role in aging skeletal muscle." in: Age (Dordrecht, Netherlands), Vol. 35, Issue 2, pp. 353-70, (2013) (PubMed).

Zhang, Birbrair, Delbono: "Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis." in: Cytoskeleton (Hoboken, N.J.), Vol. 70, Issue 3, pp. 134-47, (2013) (PubMed).

Chaze, Meunier, Chambon, Jurie, Picard: "Proteome dynamics during contractile and metabolic differentiation of bovine foetal muscle." in: Animal : an international journal of animal bioscience, Vol. 3, Issue 7, pp. 980-1000, (2012) (PubMed).

Zhao, Jiang, Han, Bian, Li, Huang, Kong, Li: "A novel mutation in TNNT3 associated with Sheldon-Hall syndrome in a Chinese family with vertical talus." in: European journal of medical genetics, Vol. 54, Issue 3, pp. 351-3, (2011) (PubMed).

Aliases for TNNT3 抗体

troponin T3, fast skeletal type (TNNT3) 抗体
troponin T3, skeletal, fast (Tnnt3) 抗体
troponin T3, fast skeletal type S homeolog (tnnt3.S) 抗体
troponin T3, fast skeletal type (Tnnt3) 抗体
troponin T type 3 (skeletal, fast) (TNNT3) 抗体
troponin T1, slow skeletal type (TNNT1) 抗体
fTnT 抗体
Tnnt3 抗体
tnnt3a 抗体
Tnt 抗体
TNTF 抗体
TnTf 抗体
You are here:
客服