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TNFRSF18 抗体 (AA 178-241)

TNFRSF18 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518961
发货至: 中国
  • 抗原 See all TNFRSF18 抗体
    TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
    抗原表位
    • 15
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 178-241
    适用
    小鼠, 大鼠
    宿主
    • 32
    • 25
    • 24
    克隆类型
    • 49
    • 30
    • 2
    多克隆
    标记
    • 44
    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF18 antibody is un-conjugated
    应用范围
    • 40
    • 33
    • 25
    • 14
    • 14
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 18(TNFRSF18) detection. Tested with WB in Human,Mouse,Rat.
    交叉反应 (详细)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 18(TNFRSF18) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: TNF receptor superfamily member 18
    Protein Name: Tumor necrosis factor receptor superfamily member 18
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived human TNFRSF18 recombinant protein (Position: L178-V241). Human TNFRSF18 shares 76.2% amino acid (aa) sequence identity with mouse TNFRSF18.
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF18 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
    别名
    TNFRSF18 (TNFRSF18 产品)
    别名
    GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody
    背景
    Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. It is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

    Synonyms: Tumor necrosis factor receptor superfamily member 18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, CD357, TNFRSF18, AITR, GITR, UNQ319/PRO364
    基因ID
    8784
    UniProt
    Q9Y5U5
    途径
    Cancer Immune Checkpoints
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