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IL1RN 抗体 (AA 26-177)

IL1RN 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518923
发货至: 中国
  • 抗原 See all IL1RN 抗体
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    抗原表位
    • 28
    • 16
    • 11
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    AA 26-177
    适用
    • 78
    • 34
    • 16
    • 9
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    • 4
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    宿主
    • 96
    • 33
    • 5
    • 3
    • 1
    • 1
    克隆类型
    • 103
    • 36
    多克隆
    标记
    • 69
    • 28
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL1RN antibody is un-conjugated
    应用范围
    • 115
    • 52
    • 37
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    • 18
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    • 13
    • 8
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    Western Blotting (WB), ELISA
    原理
    Rabbit IgG polyclonal antibody for Interleukin-1 receptor antagonist protein(IL1RN) detection. Tested with WB, ELISA in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Interleukin-1 receptor antagonist protein(IL1RN) detection. Tested with WB, ELISA in Human.
    Gene Name: interleukin 1 receptor antagonist
    Protein Name: Interleukin-1 receptor antagonist protein
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived human IL1RA recombinant protein (Position: R26-E177). Human IL1RA shares 77% and 75.5% amino acid (aa) sequence identity with mouse and rat IL1RA, respectively.
    亚型
    IgG
    Top Product
    Discover our top product IL1RN Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Lu, Jiang, Cao, Zhang, Zhang, Ji, Gao: "TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling." in: Pain, Vol. 155, Issue 12, pp. 2618-29, (2015) (PubMed).

  • 抗原
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    别名
    IL1RN (IL1RN 产品)
    别名
    DIRA antibody, ICIL-1RA antibody, IL-1RN antibody, IL-1ra antibody, IL-1ra3 antibody, IL1F3 antibody, IL1RA antibody, IRAP antibody, MVCD4 antibody, IRAP1 antibody, IL1RN antibody, IL-1RA antibody, F630041P17Rik antibody, interleukin 1 receptor antagonist antibody, interleukin 1 receptor antagonist-like antibody, IL1RN antibody, Il1rn antibody, IL1RNL antibody
    背景
    The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Synonyms: Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, Anakinra, IL1RN, IL1F3, IL1RA
    基因ID
    3557
    UniProt
    P18510
    途径
    NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints
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