Nephrin 抗体 (AA 1084-1241)
(2 references)-
- 抗原 See all Nephrin (NPHS1) 抗体
- Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
-
抗原表位
- AA 1084-1241
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Nephrin antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Nephrin(NPHS1) detection. Tested with WB in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for Nephrin(NPHS1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nephrosis 1, congenital, Finnish type (nephrin)
Protein Name: Nephrin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human Nephrin recombinant protein (Position: V1084-V1241). Human Nephrin shares 79.9% and 75.3% amino acid (aa) sequence identity with mouse and rat Nephrin, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product NPHS1 Primary Antibody
-
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 23-92) antibody
NPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 451-550) antibodyNPHS1 适用: 人, 小鼠, 大鼠, 犬 FACS 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 27-234) antibodyNPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 27-234) antibodyNPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 23-257) antibodyNPHS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 1191-1219), (Tyr1210) antibodyNPHS1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB28264 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (C-Term) antibodyNPHS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 39-144) antibodyNPHS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 39-106) antibodyNPHS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 33-122) antibodyNPHS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
-
: "Effect of simvastatin on the expression of nephrin, podocin, and vascular endothelial growth factor (VEGF) in podocytes of diabetic rat." in: International journal of clinical and experimental medicine, Vol. 8, Issue 10, pp. 18225-34, (2016) (PubMed).
: "Effect of Cordyceps sinensis and Tripterygium wilfordii polyglycosidium on podocytes in rats with diabetic nephropathy." in: Experimental and therapeutic medicine, Vol. 7, Issue 6, pp. 1465-1470, (2014) (PubMed).
-
: "Effect of simvastatin on the expression of nephrin, podocin, and vascular endothelial growth factor (VEGF) in podocytes of diabetic rat." in: International journal of clinical and experimental medicine, Vol. 8, Issue 10, pp. 18225-34, (2016) (PubMed).
-
- 抗原
- Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
- 别名
- NPHS1 (NPHS1 产品)
- 别名
- NPHS1 antibody, nphs1l antibody, nphs1 antibody, CNF antibody, NPHN antibody, nephrin antibody, NephrinB antibody, NPHS1, nephrin antibody, nephrosis 1, congenital, Finnish type (nephrin) antibody, NPHS1 nephrin S homeolog antibody, nephrin antibody, NPHS1 nephrin antibody, nephrosis 1, nephrin antibody, NPHS1 antibody, nphs1 antibody, nphs1.S antibody, LOC5579127 antibody, Nphs1 antibody
- 背景
-
NPHS1, also called Nephrin, is mapped to 19q13.12. This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. It gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. A defect in the gene for nephrin, NPHS1, is associated with congenital nephrotic syndrome of the Finnish type and causes massive amounts of protein to be leaked into the urine, orproteinuria. NPHS1 is also required for cardiovascular development.
Synonyms: CNF | Nephrin | NPHN | NPHS 1 | NPHS1 | O60500 - 基因ID
- 4868
- UniProt
- O60500
- 途径
- Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development
-
