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Angiotensin I Converting Enzyme 1 抗体 (N-Term)

ACE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518713
发货至: 中国
  • 抗原 See all Angiotensin I Converting Enzyme 1 (ACE) 抗体
    Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
    抗原表位
    • 16
    • 16
    • 5
    • 5
    • 4
    • 4
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    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 130-144, N-Term
    适用
    • 102
    • 51
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    • 22
    • 12
    • 8
    • 3
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    • 1
    • 1
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    • 1
    宿主
    • 89
    • 27
    • 3
    • 1
    • 1
    克隆类型
    • 82
    • 39
    多克隆
    标记
    • 59
    • 16
    • 7
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiotensin I Converting Enzyme 1 antibody is un-conjugated
    应用范围
    • 95
    • 43
    • 43
    • 31
    • 26
    • 26
    • 15
    • 10
    • 10
    • 6
    • 6
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Angiotensin-converting enzyme(ACE) detection. Tested with WB in Human,Mouse.
    序列
    ANLPLAKRQQ YNALL
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Angiotensin-converting enzyme(ACE) detection. Tested with WB in Human,Mouse.
    Gene Name: angiotensin I converting enzyme
    Protein Name: Angiotensin-converting enzyme
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human Angiotensin Converting Enzyme 1(130-144aa ANLPLAKRQQYNALL), different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ACE Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Yan, Shen: "Aliskiren has chondroprotective efficacy in a rat model of osteoarthritis through suppression of the local renin-angiotensin system." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 3965-3973, (2018) (PubMed).

  • 抗原
    Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
    别名
    ACE (ACE 产品)
    别名
    ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, AW208573 antibody, Dcp1 antibody, StsRR92 antibody, dcp antibody, ace1 antibody, dcp1 antibody, xace antibody, cd143 antibody, ACE antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 antibody, angiotensin-converting enzyme antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 antibody, angiotensin-converting enzyme-like antibody, ACE antibody, Ace antibody, ace antibody, CpipJ_CPIJ009106 antibody, ACE3 antibody, LOC101824864 antibody
    背景
    Angiotensin I converting enzyme(ACE), also called DCP or CD143 is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is though to play a critical role in blood pressure regulation. This gene is mapped to 17q23.3. This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies.

    Synonyms: ACE 1 antibody|ACE antibody|ACE T antibody|ACE_HUMAN antibody|ACE1 antibody|Angiotensin converting enzyme somatic isoform antibody|Angiotensin converting enzyme testis specific isoform antibody|Angiotensin I converting enzyme 1 antibody|Angiotensin I converting enzyme antibody|Angiotensin I converting enzyme peptidyl dipeptidase A 1 antibody|Angiotensin-converting enzyme antibody|Carboxycathepsin antibody|CD 143 antibody|CD143 antibody|CD143 antigen antibody|DCP 1 antibody|DCP antibody|DCP1 antibody|Dipeptidyl carboxypeptidase 1 antibody|Dipeptidyl carboxypeptidase I antibody|Kininase II antibody|MGC26566 antibody|MVCD3 antibody|Peptidase P antibody|Peptidyl dipeptidase A antibody|soluble form antibody|Testicular ECA antibody
    UniProt
    P12821
    途径
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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