B4GALT1 抗体 (C-Term)
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- 抗原 See all B4GALT1 抗体
- B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This B4GALT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- GRCRMIRHSR DKKNEPNPQR FDRIAHTKET MLSDGLNSLT YQVLDVQRYP
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human B4GALT1
- Top Product
- Discover our top product B4GALT1 Primary Antibody
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anti-UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (C-Term) antibody
B4GALT1 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (C-Term) antibodyB4GALT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (AA 50-215) antibodyB4GALT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (AA 329-358), (C-Term) antibodyB4GALT1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB21685 unconjugated
anti-UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) (C-Term) antibodyB4GALT1 适用: 人, 小鼠, Cow, 猴, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1) antibodyB4GALT1 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
- 别名
- B4GALT1 (B4GALT1 产品)
- 别名
- B4GAL-T1 antibody, CDG2D antibody, GGTB2 antibody, GT1 antibody, GTB antibody, beta4Gal-T1 antibody, B-1,4-GalT antibody, B-1,4-GalT1 antibody, GalT antibody, Ggtb antibody, Ggtb2 antibody, b4Gal-T1 antibody, beta-1,4-GalT antibody, beta-1,4-GalT1 antibody, beta-1,4-galactosyltransferase 1 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 antibody, B4GALT1 antibody, B4galt1 antibody
- 背景
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This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.
Alias Symbols: GT1, GTB, CDG2D, GGTB2, B4GAL-T1, beta4Gal-T1,
Protein Size: 398 - 基因ID
- 2683
- NCBI登录号
- NM_001497, NP_001488
- UniProt
- P15291
- 途径
- Glycosaminoglycan Metabolic Process
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