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B4GALT1 抗体

B4GALT1 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
产品编号 ABIN7490650
发货至: 中国
  • 抗原 See all B4GALT1 抗体
    B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
    片段
    Fc fragment
    适用
    • 28
    • 9
    • 1
    • 1
    • 1
    宿主
    • 26
    • 2
    克隆类型
    • 26
    • 2
    Chimeric
    标记
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This B4GALT1 antibody is un-conjugated
    应用范围
    • 21
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    产品特性
    Rabbit/Human Fc chimeric IgG1
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product B4GALT1 Primary Antibody
  • 应用备注
    Flow Cyt  1:100
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
    别名
    B4GALT1 (B4GALT1 产品)
    别名
    B4GAL-T1 antibody, CDG2D antibody, GGTB2 antibody, GT1 antibody, GTB antibody, beta4Gal-T1 antibody, B-1,4-GalT antibody, B-1,4-GalT1 antibody, GalT antibody, Ggtb antibody, Ggtb2 antibody, b4Gal-T1 antibody, beta-1,4-GalT antibody, beta-1,4-GalT1 antibody, beta-1,4-galactosyltransferase 1 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 antibody, B4GALT1 antibody, B4galt1 antibody
    背景
    GGTB2, Beta4Gal-T1, b4Gal-T1, Nal synthase,
    Description: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose D-glucose UDP lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.
    UniProt
    P15291
    途径
    Glycosaminoglycan Metabolic Process
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