B4GALT1 抗体 (AA 50-215)
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- 抗原 See all B4GALT1 抗体
- B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
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抗原表位
- AA 50-215
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This B4GALT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- LPQLVGVSTP LQGGSNSAAA IGQSSGELRT GGARPPPPLG ASSQPRPGGD SSPVVDSGPG PASNLTSVPV PHTTALSLPA CPEESPLLVG PMLIEFNMPV DLELVAKQNP NVKMGGRYAP RDCVSPHKVA IIIPFRNRQE HLKYWLYYLH PVLQRQQLDY GIYVIN
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-215 of human B4GALT1 (NP_001488.2).
- 亚型
- IgG
- Top Product
- Discover our top product B4GALT1 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))
- 别名
- B4GALT1 (B4GALT1 产品)
- 别名
- B4GAL-T1 antibody, CDG2D antibody, GGTB2 antibody, GT1 antibody, GTB antibody, beta4Gal-T1 antibody, B-1,4-GalT antibody, B-1,4-GalT1 antibody, GalT antibody, Ggtb antibody, Ggtb2 antibody, b4Gal-T1 antibody, beta-1,4-GalT antibody, beta-1,4-GalT1 antibody, beta-1,4-galactosyltransferase 1 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 antibody, B4GALT1 antibody, B4galt1 antibody
- 背景
- This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.,B4GALT1,B4GAL-T1,CDG2D,GGTB2,GT1,GTB,beta4Gal-T1,beta-1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Angiogenesis,B4GALT1
- 分子量
- 42 kDa/43 kDa
- 基因ID
- 2683
- UniProt
- P15291
- 途径
- Glycosaminoglycan Metabolic Process
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