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APC 抗体 (Middle Region)
APC
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
APC抗体详情
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抗原
See all APC 抗体
APC
(Adenomatous Polyposis Coli (APC))
抗原表位
All epitopes for APC 抗体
Middle Region
适用
All reactivities for APC 抗体
人
宿主
All hosts for APC 抗体
兔
克隆类型
All clonalities for APC 抗体
多克隆
标记
All conjugates for APC 抗体
This APC antibody is un-conjugated
应用范围
All applications for APC 抗体
Western Blotting (WB)
序列
SETFDNIDNL SPKASHRSKQ RHKQSLYGDY VFDTNRHDDN RSDNFNTGNM
纯化方法
Affinity purified
免疫原
The immunogen is a synthetic peptide directed towards the middle region of human APC
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Discover our top product APC Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
APC目标详情
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抗原
APC
(Adenomatous Polyposis Coli (APC))
别名
APC (APC 产品 )
别名
dp2 antibody, dp3 antibody, fap antibody, fpc antibody, xapc antibody, dp2.5 antibody, AI047805 antibody, AU020952 antibody, AW124434 antibody, CC1 antibody, Min antibody, mAPC antibody, BTPS2 antibody, DP2 antibody, DP2.5 antibody, DP3 antibody, GS antibody, PPP1R46 antibody, RATAPC antibody, APC1 antibody, APC, WNT signaling pathway regulator antibody, adenomatous polyposis coli antibody, adenomatous polyposis coli protein, putative antibody, adenomatosis polyposis coli antibody, adenomatous polyposis coli L homeolog antibody, APC antibody, apc antibody, Smp_139190 antibody, Apc antibody, apc.L antibody
背景
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. Alias Symbols: GS, DP2, DP3, BTPS2, DP2.5, PPP1R46 Protein Size: 1304
基因ID
324
NCBI登录号
NM_000038 , NP_000029
UniProt
E9PFT7
途径
WNT signaling , Stem Cell Maintenance , Cell-Cell Junction Organization
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