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14-3-3 sigma/SFN 抗体 (N-Term)

SFN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5516411
发货至: 中国
  • 抗原 See all 14-3-3 sigma/SFN (SFN) 抗体
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    抗原表位
    • 15
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    N-Term
    适用
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    宿主
    • 93
    • 9
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    克隆类型
    • 88
    • 17
    多克隆
    标记
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    This 14-3-3 sigma/SFN antibody is un-conjugated
    应用范围
    • 86
    • 44
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    Western Blotting (WB)
    序列
    IEQKSNEEGS EEKGPEVREY REKVETELQG VCDTVLGLLD SHLIKEAGDA
    产品特性
    This is a rabbit polyclonal antibody against SFN. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human SFN
    Top Product
    Discover our top product SFN Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
    别名
    SFN (SFN 产品)
    别名
    YWHAS antibody, Er antibody, Mme1 antibody, Ywhas antibody, stratifin antibody, SFN antibody, Sfn antibody
    背景
    SFN is a p53-regulated inhibitor of G2/M progression. It is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. It binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. It may also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

    Alias Symbols: SFN, HME1,

    Protein Interaction Partner: FAM9B, RAB3IP, LONRF1, CCDC102B, ZC2HC1C, DTL, FAM53C, MKRN3, FOXO4, MAGEA1, CCNH, SIK3, ZFYVE19, YWHAZ, VCL, UBE2V1, SNRPF, UBE2R2, PAK2, G6PD, TARDBP, EGFR, BAD, MARK3, HDAC7, HDAC5, HDAC4, RAF1, CDC25C, MST1R, ABL1, HNRNPD, ATF2, TRIM32, COPS6, UBC, TP

    Protein Size: 248
    基因ID
    2810
    NCBI登录号
    NP_006133
    UniProt
    P31947
    途径
    p53 Pathway, Myometrial Relaxation and Contraction
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