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MBD4 抗体 (Middle Region)

MBD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5516287
发货至: 中国
  • 抗原 See all MBD4 抗体
    MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))
    抗原表位
    • 9
    • 9
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 34
    • 5
    • 3
    • 1
    宿主
    • 33
    • 1
    • 1
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 18
    • 4
    • 4
    • 3
    • 3
    • 3
    This MBD4 antibody is un-conjugated
    应用范围
    • 28
    • 24
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    TSLKPEDFDF TVLSKRGIKS RYKDCSMAAL TSHLQNQSNN SNWNLRTRSK
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MBD4
    Top Product
    Discover our top product MBD4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))
    别名
    MBD4 (MBD4 产品)
    别名
    MED1 antibody, Med1 antibody, methyl-CpG binding domain 4, DNA glycosylase antibody, methyl-CpG binding domain protein 4 antibody, methyl-CpG binding domain 4 DNA glycosylase antibody, MBD4 antibody, Mbd4 antibody
    背景
    The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Alias Symbols: MED1

    Protein Size: 580
    基因ID
    8930
    NCBI登录号
    NM_001276270, NP_001263199
    UniProt
    O95243
    途径
    DNA Damage Repair
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