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TYROBP 抗体 (Middle Region)

TYROBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515952
发货至: 中国
  • 抗原 See all TYROBP 抗体
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    抗原表位
    • 16
    • 15
    • 15
    • 11
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 49
    • 20
    • 4
    宿主
    • 66
    • 1
    • 1
    克隆类型
    • 59
    • 9
    多克隆
    标记
    • 22
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TYROBP antibody is un-conjugated
    应用范围
    • 41
    • 30
    • 26
    • 26
    • 21
    • 18
    • 12
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    IALAVYFLGR LVPRGRGAAE AATRKQRITE TESPYQELQG QRSDVYSDLN
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human TYROBP
    Top Product
    Discover our top product TYROBP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    TYROBP (TYROBP 产品)
    别名
    TYROBP antibody, DAP12 antibody, tyrpbp antibody, Karap antibody, KARAP antibody, PLOSL antibody, Ly83 antibody, dap12 antibody, TYRO protein tyrosine kinase binding protein antibody, Tyro protein tyrosine kinase binding protein antibody, TYROBP antibody, tyrobp antibody, Tyrobp antibody
    背景
    This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.

    Alias Symbols: DAP12, KARAP, PLOSL

    Protein Size: 144
    基因ID
    7305
    NCBI登录号
    NP_001166985
    UniProt
    K7ES93
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