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TYROBP 抗体

TYROBP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7192969
发货至: 中国
  • 抗原 See all TYROBP 抗体
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    适用
    • 48
    • 20
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    宿主
    • 65
    • 1
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    克隆类型
    • 58
    • 9
    多克隆
    标记
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    This TYROBP antibody is un-conjugated
    应用范围
    • 41
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    Immunohistochemistry (IHC), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of Human TYROBP
    亚型
    IgG
    Top Product
    Discover our top product TYROBP Primary Antibody
  • 应用备注
    ELISA:1:1000-1:10000, IHC:1:25-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    TYROBP (TYROBP 产品)
    别名
    TYROBP antibody, DAP12 antibody, tyrpbp antibody, Karap antibody, KARAP antibody, PLOSL antibody, Ly83 antibody, dap12 antibody, TYRO protein tyrosine kinase binding protein antibody, Tyro protein tyrosine kinase binding protein antibody, TYROBP antibody, tyrobp antibody, Tyrobp antibody
    背景

    Background: This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.

    Aliases: DAP 12 antibody, DAP12 antibody, DNAX activation protein 12 antibody, DNAX-activation protein 12 antibody, KAR-associated protein antibody, KARAP antibody, Killer activating receptor associated protein antibody, Killer-activating receptor-associated protein antibody, PLOSL antibody, TYOBP_HUMAN antibody, TYRO protein tyrosine kinase binding protein antibody, TYRO protein tyrosine kinase-binding protein antibody, TYROBP antibody

    UniProt
    O43914
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