TYROBP 抗体
(TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010].
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TYROBP 抗体 by 适用
Find TYROBP 抗体 for a variety of species such as anti-Human TYROBP, anti-Mouse TYROBP, anti-Rat TYROBP. The species listed below are among those available. Click on a link to go to the corresponding products.
TYROBP 抗体 by 应用范围
Find TYROBP 抗体 validated for a specific application such as WB, FACS, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
TYROBP 抗体 by 抗体来源
Find TYROBP 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
TYROBP 抗体 by 抗原表位
Find TYROBP 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
TYROBP 抗体 by 克隆形成能力
Find available monoclonal or polyclonal TYROBP 抗体. Click on a link to go to the corresponding products.
TYROBP 抗体 by 克隆
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Popular TYROBP 抗体
Product
Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Mouse, Rat
Application
IHC
Validations
- (2)
Cat. No.
ABIN7261337
Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA
Validations
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Cat. No.
ABIN6265826
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
IP
Validations
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Cat. No.
ABIN550357
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, FACS, IHC (p)
Validations
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Cat. No.
ABIN653819
Quantity
400 μL
Datasheet
Datasheet
Reactivity
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Application
WB, FACS, IHC (p), EIA
Validations
- (3)
Cat. No.
ABIN955408
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN5534118
Quantity
400 μL
Datasheet
Datasheet
Reactivity
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Application
WB, FACS
Validations
- (1)
Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IP
Validations
- (1)
Cat. No.
ABIN306916
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, FACS, IHC, IHC (p)
Validations
- (1)
Cat. No.
ABIN1978257
Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
WB
Validations
- (1)
Cat. No.
ABIN7271115
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC (p)
Validations
- (2)
Cat. No.
ABIN1740506
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1714723
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
Cat. No.
ABIN1713480
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1701221
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our TYROBP 抗体
: "Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 63, (2019) (PubMed).: "The female reproductive tract contains multiple innate sialic acid-binding immunoglobulin-like lectins (Siglecs) that facilitate sperm survival." in: The Journal of biological chemistry, Vol. 294, Issue 31, pp. 11910-11919, (2019) (PubMed).
: "CD33 modulates TREM2: convergence of Alzheimer loci." in: Nature neuroscience, Vol. 18, Issue 11, pp. 1556-8, (2016) (PubMed).
: "Th2-M2 immunity in lesions of muscular sarcoidosis and macrophagic myofasciitis." in: Neuropathology and applied neurobiology, Vol. 41, Issue 7, pp. 952-63, (2015) (PubMed).
: "The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function." in: Immunology today, Vol. 21, Issue 12, pp. 611-4, (2001) (PubMed).
: "Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts." in: Nature genetics, Vol. 25, Issue 3, pp. 357-61, (2000) (PubMed).
: "Combined natural killer cell and dendritic cell functional deficiency in KARAP/DAP12 loss-of-function mutant mice." in: Immunity, Vol. 13, Issue 3, pp. 355-64, (2000) (PubMed).
Aliases for TYROBP 抗体
TYRO protein tyrosine kinase binding protein (TYROBP) 抗体TYRO protein tyrosine kinase binding protein (tyrobp) 抗体
Tyro protein tyrosine kinase binding protein (Tyrobp) 抗体
TYRO protein tyrosine kinase binding protein (Tyrobp) 抗体
DAP12 抗体
dap12 抗体
Karap 抗体
KARAP 抗体
Ly83 抗体
PLOSL 抗体
TYROBP 抗体
tyrpbp 抗体
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