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PABPN1 抗体 (C-Term)
PABPN1
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
PABPN1抗体详情
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抗原
See all PABPN1 抗体
PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
抗原表位
All epitopes for PABPN1 抗体
C-Term
适用
All reactivities for PABPN1 抗体
人
宿主
All hosts for PABPN1 抗体
兔
克隆类型
All clonalities for PABPN1 抗体
多克隆
标记
All conjugates for PABPN1 抗体
This PABPN1 antibody is un-conjugated
应用范围
All applications for PABPN1 抗体
Western Blotting (WB)
序列
NRPGISTTDR GFPRARYRAR TTNYNSSRSR FYSGFNSRPR GRVYRGRARA
纯化方法
Affinity purified
免疫原
The immunogen is a synthetic peptide directed towards the C terminal region of human PABPN1
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Discover our top product PABPN1 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
PABPN1目标详情
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抗原
PABPN1
(Poly A Binding Protein Nuclear 1 (PABPN1))
别名
PABPN1 (PABPN1 产品 )
别名
OPMD antibody, PAB2 antibody, PABII antibody, PABP-2 antibody, PABP2 antibody, Pabp3 antibody, mPABII antibody, ARABIDOPSIS POLY(A) BINDING 2 antibody, ATPAB2 antibody, F28A23.130 antibody, F28A23_130 antibody, POLY(A) BINDING PROTEIN 2 antibody, POLY(A)-BINDING PROTEIN 2 antibody, poly(A) binding protein 2 antibody, opmd antibody, pab2 antibody, pabp2 antibody, pabpii antibody, pabpn1 antibody, Pabpn1 antibody, Poly(A)-binding protein 2 antibody, fb19c03 antibody, wu:fb17e03 antibody, wu:fb18c06 antibody, wu:fb19c03 antibody, zgc:85979 antibody, zgc:92452 antibody, poly(A) binding protein nuclear 1 antibody, poly(A) binding protein, nuclear 1 antibody, poly(A) binding protein 2 antibody, poly(A) binding protein, nuclear 1 S homeolog antibody, poly(A) binding protein, nuclear 1 L homeolog antibody, polyadenylate-binding protein 2 antibody, poly(A) binding protein Pab2 antibody, PABPN1 antibody, Pabpn1 antibody, PAB2 antibody, pabpn1.S antibody, pabpn1.L antibody, LOC100728725 antibody, pab2 antibody, pabpn1 antibody
背景
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. Alias Symbols: OPMD, PAB2, PABII, PABP2, PABP-2, Protein Size: 333
基因ID
8106
NCBI登录号
NM_001199839 , NP_004634
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