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PABPN1 抗体 (AA 1-100)

PABPN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6145153
发货至: 中国
  • 抗原 See all PABPN1 抗体
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    抗原表位
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    AA 1-100
    适用
    • 41
    • 20
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    宿主
    • 41
    克隆类型
    • 30
    • 11
    多克隆
    标记
    • 17
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PABPN1 antibody is un-conjugated
    应用范围
    • 26
    • 13
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MAAAAAAAAA AGAAGGRGSG PGRRRHLVPG AGGEAGEGAP GGAGDYGNGL ESEELEPEEL LLEPEPEPEP EEEPPRPRAP PGAPGPGPGS GAPGSQEEEE
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PABPN1 (NP_004634.1).
    亚型
    IgG
    Top Product
    Discover our top product PABPN1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:1000
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Shi, Zhang, Wu, He, Wang, Yin, Tian, Li, Cheng: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).

  • 抗原
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    别名
    PABPN1 (PABPN1 产品)
    别名
    OPMD antibody, PAB2 antibody, PABII antibody, PABP-2 antibody, PABP2 antibody, Pabp3 antibody, mPABII antibody, ARABIDOPSIS POLY(A) BINDING 2 antibody, ATPAB2 antibody, F28A23.130 antibody, F28A23_130 antibody, POLY(A) BINDING PROTEIN 2 antibody, POLY(A)-BINDING PROTEIN 2 antibody, poly(A) binding protein 2 antibody, opmd antibody, pab2 antibody, pabp2 antibody, pabpii antibody, pabpn1 antibody, Pabpn1 antibody, Poly(A)-binding protein 2 antibody, fb19c03 antibody, wu:fb17e03 antibody, wu:fb18c06 antibody, wu:fb19c03 antibody, zgc:85979 antibody, zgc:92452 antibody, poly(A) binding protein nuclear 1 antibody, poly(A) binding protein, nuclear 1 antibody, poly(A) binding protein 2 antibody, poly(A) binding protein, nuclear 1 S homeolog antibody, poly(A) binding protein, nuclear 1 L homeolog antibody, polyadenylate-binding protein 2 antibody, poly(A) binding protein Pab2 antibody, PABPN1 antibody, Pabpn1 antibody, PAB2 antibody, pabpn1.S antibody, pabpn1.L antibody, LOC100728725 antibody, pab2 antibody, pabpn1 antibody
    背景
    This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.,PABPN1,OPMD,PAB2,PABII,PABP-2,PABP2,Epigenetics & Nuclear Signaling,RNA Binding,PABPN1
    分子量
    31 kDa/32 kDa/37 kDa
    基因ID
    8106
    UniProt
    Q86U42
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