PABPN1 抗体
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- 抗原 See all PABPN1 抗体
- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PABPN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to PABPN1 (poly(A) binding protein, nuclear 1)
PABPN1 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human PABPN1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product PABPN1 Primary Antibody
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anti-Poly A Binding Protein Nuclear 1 (PABPN1) antibody
PABPN1 适用: 人, 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) antibodyPABPN1 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) antibodyPABPN1 适用: 人 WB, ELISA, IF, IHC, FACS 宿主: 兔 Monoclonal 6C3 unconjugated Recombinant Antibody
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (N-Term) antibodyPABPN1 适用: 人, 小鼠, 犬, 大鼠, 兔, Cow, 豚鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (N-Term) antibodyPABPN1 适用: 人, 犬, 大鼠, 兔, Cow, 豚鼠, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (AA 1-100) antibodyPABPN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (C-Term) antibodyPABPN1 适用: 人, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Mouse brain , Jurkat
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.49 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
- 别名
- poly(A) binding protein nuclear 1 (PABPN1 产品)
- 别名
- OPMD antibody, PAB2 antibody, PABII antibody, PABP-2 antibody, PABP2 antibody, Pabp3 antibody, mPABII antibody, ARABIDOPSIS POLY(A) BINDING 2 antibody, ATPAB2 antibody, F28A23.130 antibody, F28A23_130 antibody, POLY(A) BINDING PROTEIN 2 antibody, POLY(A)-BINDING PROTEIN 2 antibody, poly(A) binding protein 2 antibody, opmd antibody, pab2 antibody, pabp2 antibody, pabpii antibody, pabpn1 antibody, Pabpn1 antibody, Poly(A)-binding protein 2 antibody, fb19c03 antibody, wu:fb17e03 antibody, wu:fb18c06 antibody, wu:fb19c03 antibody, zgc:85979 antibody, zgc:92452 antibody, poly(A) binding protein nuclear 1 antibody, poly(A) binding protein, nuclear 1 antibody, poly(A) binding protein 2 antibody, poly(A) binding protein, nuclear 1 S homeolog antibody, poly(A) binding protein, nuclear 1 L homeolog antibody, polyadenylate-binding protein 2 antibody, poly(A) binding protein Pab2 antibody, PABPN1 antibody, Pabpn1 antibody, PAB2 antibody, pabpn1.S antibody, pabpn1.L antibody, LOC100728725 antibody, pab2 antibody, pabpn1 antibody
- 背景
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This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.
Cellular Localization: Nucleus (By similarity) , Cytoplasm (By similarity) - 分子量
- 33 kDa
- 基因ID
- 8106
- UniProt
- Q86U42
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