-
- 抗原 See all APH1A 抗体
- APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This APH1A antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit polyclonal antibody raised against synthetic peptide of APH1A.
- 交叉反应
- 人
- 产品特性
- Antibody Reactive Against Synthetic Peptide.
- 免疫原
- A synthetic peptide corresponding to human APH1A.
- Top Product
- Discover our top product APH1A Primary Antibody
-
-
- 应用备注
-
Western Blot (3-10 μg/mL)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- In PBS (0.1 % proclin, 2.0 % Block Ace)
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
-
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
-
-
The role of presenilin cofactors in the gamma-secretase complex." in: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).
: "Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling." in: Nature reviews. Molecular cell biology, Vol. 3, Issue 9, pp. 673-84, (2002) (PubMed).
: "APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 2, pp. 775-9, (2002) (PubMed).
: "aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation." in: Developmental cell, Vol. 3, Issue 1, pp. 85-97, (2002) (PubMed).
: "Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45013-9, (2002) (PubMed).
: "
-
The role of presenilin cofactors in the gamma-secretase complex." in: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).
-
- 抗原
- APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
- 别名
- APH1A (APH1A 产品)
- 别名
- 6530402N02Rik antibody, APH-1 antibody, APH-1A antibody, CGI-78 antibody, RGD1311546 antibody, APH-1a antibody, aph-1 homolog A, gamma-secretase subunit antibody, aph-1 homolog A, gamma secretase subunit L homeolog antibody, aph-1 homolog A, gamma secretase subunit antibody, anterior pharynx defective 1 homolog A (C. elegans) antibody, aph1 homolog A, gamma secretase subunit antibody, acylamino-acid-releasing enzyme-like antibody, APH1A antibody, aph1a.L antibody, Aph1a antibody, LOC100219182 antibody
- 基因ID
- 51107
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
-