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APH1A 抗体

APH1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN549020
发货至: 中国
  • 抗原 See all APH1A 抗体
    APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
    适用
    • 51
    • 35
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 56
    • 1
    克隆类型
    • 57
    多克隆
    标记
    • 21
    • 6
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APH1A antibody is un-conjugated
    应用范围
    • 48
    • 33
    • 14
    • 13
    • 13
    • 10
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit polyclonal antibody raised against synthetic peptide of APH1A.
    交叉反应
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    A synthetic peptide corresponding to human APH1A.
    Top Product
    Discover our top product APH1A Primary Antibody
  • 应用备注
    Western Blot (3-10 μg/mL)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In PBS (0.1 % proclin, 2.0 % Block Ace)
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Takasugi, Tomita, Hayashi, Tsuruoka, Niimura, Takahashi, Thinakaran, Iwatsubo: "The role of presenilin cofactors in the gamma-secretase complex." in: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).

    Fortini: "Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling." in: Nature reviews. Molecular cell biology, Vol. 3, Issue 9, pp. 673-84, (2002) (PubMed).

    Goutte, Tsunozaki, Hale, Priess: "APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 2, pp. 775-9, (2002) (PubMed).

    Francis, McGrath, Zhang, Ruddy, Sym, Apfeld, Nicoll, Maxwell, Hai, Ellis, Parks, Xu, Li, Gurney, Myers, Himes, Hiebsch, Ruble, Nye, Curtis: "aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation." in: Developmental cell, Vol. 3, Issue 1, pp. 85-97, (2002) (PubMed).

    Lee, Shah, Li, Yu, Han, Yu: "Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45013-9, (2002) (PubMed).

  • 抗原
    APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
    别名
    APH1A (APH1A 产品)
    别名
    6530402N02Rik antibody, APH-1 antibody, APH-1A antibody, CGI-78 antibody, RGD1311546 antibody, APH-1a antibody, aph-1 homolog A, gamma-secretase subunit antibody, aph-1 homolog A, gamma secretase subunit L homeolog antibody, aph-1 homolog A, gamma secretase subunit antibody, anterior pharynx defective 1 homolog A (C. elegans) antibody, aph1 homolog A, gamma secretase subunit antibody, acylamino-acid-releasing enzyme-like antibody, APH1A antibody, aph1a.L antibody, Aph1a antibody, LOC100219182 antibody
    基因ID
    51107
    途径
    Notch Signaling, Neurotrophin Signaling Pathway
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