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- 抗原 See all APH1A 抗体
- APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APH1A antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human APH1A (NP_001071096.1).
- 亚型
- IgG
- Top Product
- Discover our top product APH1A Primary Antibody
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anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 71-170) antibody
APH1A 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Internal Region) antibodyVerified APH1A 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (C-Term) antibodyAPH1A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 90-118) antibodyAPH1A 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 80-130) antibodyAPH1A 适用: 人, Cow, 犬, 马, 猴, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (AA 77-109), (N-Term) antibodyAPH1A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4994 unconjugated
anti-Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A) (Middle Region) antibodyAPH1A 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))
- 别名
- APH1A (APH1A 产品)
- 别名
- 6530402N02Rik antibody, APH-1 antibody, APH-1A antibody, CGI-78 antibody, RGD1311546 antibody, APH-1a antibody, aph-1 homolog A, gamma-secretase subunit antibody, aph-1 homolog A, gamma secretase subunit L homeolog antibody, aph-1 homolog A, gamma secretase subunit antibody, anterior pharynx defective 1 homolog A (C. elegans) antibody, aph1 homolog A, gamma secretase subunit antibody, acylamino-acid-releasing enzyme-like antibody, APH1A antibody, aph1a.L antibody, Aph1a antibody, LOC100219182 antibody
- 背景
- This gene encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paralogous anterior pharynx defective 1 homolog B (APH1B), along with the presenilin, nicastrin, and presenilin enhancer-2 proteins. The precise function of this seven-transmembrane-domain protein is unknown though it is suspected of facilitating the association of nicastrin and presenilin in the gamma secretase complex as well as interacting with substrates of the gamma secretase complex prior to their proteolytic processing. Polymorphisms in a promoter region of this gene have been associated with an increased risk for developing sporadic Alzheimer's disease. Alternative splicing results in multiple protein-coding and non-protein-coding transcript variants.
- 基因ID
- 51107
- UniProt
- Q96BI3
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
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