ABL1 抗体 (pTyr393, pTyr429)
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- 抗原 See all ABL1 抗体
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
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抗原表位
- pTyr393, pTyr429
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABL1 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1/ABL2.
- 序列
- DTYpTA
- 特异性
- ABL1/2 (phospho-Tyr393/429) Antibody detects endogenous levels of ABL1/2 only when phosphorylated at tyrosine393/429.
- 交叉反应
- 人, 小鼠
- 产品特性
- Antibody Reactive Against Synthetic Peptide.
- 免疫原
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y393/Y429 of human ABL1/ABL2.
- Top Product
- Discover our top product ABL1 Primary Antibody
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- 应用备注
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Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
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Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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Autoinhibition of c-Abl." in: Cell, Vol. 108, Issue 2, pp. 247-59, (2002) (PubMed).
: "JAK-STAT signaling activated by Abl oncogenes." in: Oncogene, Vol. 19, Issue 21, pp. 2523-31, (2000) (PubMed).
: "c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35631-7, (2000) (PubMed).
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Autoinhibition of c-Abl." in: Cell, Vol. 108, Issue 2, pp. 247-59, (2002) (PubMed).
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- 抗原
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
- 别名
- ABL1 (ABL1 产品)
- 别名
- ABL antibody, JTK7 antibody, bcr/abl antibody, c-ABL antibody, p150 antibody, v-abl antibody, AI325092 antibody, Abl antibody, E430008G22Rik antibody, c-Abl antibody, ABL proto-oncogene 1, non-receptor tyrosine kinase antibody, c-abl oncogene 1, non-receptor tyrosine kinase antibody, Tyrosine-protein kinase abl-1 antibody, ABL1 antibody, Abl1 antibody, abl-1 antibody, abl1 antibody
- 基因ID
- 25, 27
- 途径
- Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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