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ABL1 抗体 (pTyr393, pTyr429)

ABL1 适用: 人, 小鼠 IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN540467
发货至: 中国
  • 抗原 See all ABL1 抗体
    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
    抗原表位
    • 37
    • 33
    • 21
    • 20
    • 16
    • 15
    • 15
    • 15
    • 15
    • 15
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr393, pTyr429
    适用
    • 255
    • 142
    • 106
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 339
    • 2
    克隆类型
    • 339
    • 2
    多克隆
    标记
    • 111
    • 25
    • 23
    • 21
    • 14
    • 14
    • 14
    • 14
    • 14
    • 14
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    This ABL1 antibody is un-conjugated
    应用范围
    • 224
    • 143
    • 143
    • 142
    • 77
    • 57
    • 33
    • 32
    • 28
    • 17
    • 10
    • 3
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    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1/ABL2.
    序列
    DTYpTA
    特异性
    ABL1/2 (phospho-Tyr393/429) Antibody detects endogenous levels of ABL1/2 only when phosphorylated at tyrosine393/429.
    交叉反应
    人, 小鼠
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y393/Y429 of human ABL1/ABL2.
    Top Product
    Discover our top product ABL1 Primary Antibody
  • 应用备注
    Immunohistochemistry (1:50-1:100)
    Immunofluorescence (1:100-1:200)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Pluk, Dorey, Superti-Furga: "Autoinhibition of c-Abl." in: Cell, Vol. 108, Issue 2, pp. 247-59, (2002) (PubMed).

    Danial, Rothman: "JAK-STAT signaling activated by Abl oncogenes." in: Oncogene, Vol. 19, Issue 21, pp. 2523-31, (2000) (PubMed).

    Brasher, Van Etten: "c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35631-7, (2000) (PubMed).

  • 抗原
    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
    别名
    ABL1 (ABL1 产品)
    别名
    ABL antibody, JTK7 antibody, bcr/abl antibody, c-ABL antibody, p150 antibody, v-abl antibody, AI325092 antibody, Abl antibody, E430008G22Rik antibody, c-Abl antibody, ABL proto-oncogene 1, non-receptor tyrosine kinase antibody, c-abl oncogene 1, non-receptor tyrosine kinase antibody, Tyrosine-protein kinase abl-1 antibody, ABL1 antibody, Abl1 antibody, abl-1 antibody, abl1 antibody
    基因ID
    25, 27
    途径
    Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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