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SMAD3 抗体 (pSer423, pSer425)

SMAD3 适用: 人, 小鼠, 大鼠, Pig, 小鸡, 斑马鱼, Cow, Frog WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN539529
发货至: 中国
  • 抗原 See all SMAD3 抗体
    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
    抗原表位
    • 33
    • 28
    • 28
    • 28
    • 20
    • 14
    • 14
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer423, pSer425
    适用
    • 243
    • 150
    • 138
    • 28
    • 10
    • 9
    • 8
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig, 小鸡, 斑马鱼, Cow, Frog
    宿主
    • 234
    • 23
    克隆类型
    • 218
    • 39
    多克隆
    标记
    • 136
    • 17
    • 14
    • 13
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    This SMAD3 antibody is un-conjugated
    应用范围
    • 217
    • 117
    • 95
    • 74
    • 59
    • 55
    • 54
    • 53
    • 27
    • 13
    • 10
    • 8
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of SMAD3.
    特异性
    Reactivity occurs against human Smad3 pS423 and pS425 protein and This antibody is specific to the phosphorylated form of the protein. Reactivity with non-phosphorylated human Smad3 is minimal by ELISA and western blot. Expect reactivity against phosphorylated Smad1 and Smad5. Negligible reactivity is seen against other phosphorylated Smad family members.
    交叉反应
    小鸡, Cow, Frog, 人, 小鼠, Pig, 大鼠, 斑马鱼
    产品特性
    Antibody Reactive Against Synthetic Peptide.
    免疫原
    Synthetic phosphopeptide corresponding to residues surrounding S423/S425 of human SMAD3.
    Top Product
    Discover our top product SMAD3 Primary Antibody
  • 应用备注
    ELISA (1:75000-1:300000)
    Western Blot (1:2000-1:20000)
    Immunohistochemistry (1:500)
    The optimal working dilution should be determined by the end user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Zhang, Jiang, Tian, Wang, Zhao, Wang, Li, Liu, Li, Zhang, Guan: "CB2R orchestrates fibrogenesis through regulation of inflammatory response during the repair of skeletal muscle contusion." in: International journal of clinical and experimental pathology, Vol. 8, Issue 4, pp. 3491-502, (2015) (PubMed).

    Yamashita, Fatyol, Jin, Wang, Liu, Zhang: "TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta." in: Molecular cell, Vol. 31, Issue 6, pp. 918-24, (2008) (PubMed).

    Shi, Massagué: "Mechanisms of TGF-beta signaling from cell membrane to the nucleus." in: Cell, Vol. 113, Issue 6, pp. 685-700, (2003) (PubMed).

    Derynck, Zhang: "Smad-dependent and Smad-independent pathways in TGF-beta family signalling." in: Nature, Vol. 425, Issue 6958, pp. 577-84, (2003) (PubMed).

  • 抗原
    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
    别名
    SMAD3 (SMAD3 产品)
    别名
    HSPC193 antibody, HsT17436 antibody, JV15-2 antibody, LDS1C antibody, LDS3 antibody, MADH3 antibody, madh3 antibody, madh3a antibody, smad3 antibody, wu:fa99e03 antibody, XSmad3 antibody, XenMLP antibody, Xmad3 antibody, madh3-A antibody, Madh3 antibody, AU022421 antibody, Smad 3 antibody, mad3 antibody, madh3b antibody, zgc:92234 antibody, SMAD family member 3 antibody, SMAD family member 3a antibody, SMAD family member 3 L homeolog antibody, SMAD family member 3b antibody, SMAD3 antibody, smad3a antibody, smad3.L antibody, Smad3 antibody, smad3b antibody
    基因ID
    4088
    途径
    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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