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- 抗原 See all MARK2 抗体
- MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
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抗原表位
- pThr595
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MARK2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- 原理
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of MARK2.
- 特异性
- Reactivity occurs against human MARK2 pT595 protein and This antibody is specific to the phosphorylated form of the protein. Reactivity with non-phosphorylated human MARK2 is minimal by ELISA. Expect at least partial reactivity with other isoforms of MARK. The immunogen sequence is present in all forms identified to date and localizes to T595 on MARK2, T587 on MARK3, T591 on MARK1 and T568 on MARK4.
- 交叉反应
- Cow, 犬, 人, 小鼠, 大鼠
- 产品特性
- Antibody Reactive Against Synthetic Peptide.
- 免疫原
- Synthetic phosphopeptide corresponding to residues surrounding T595 of human MARK2.
- Top Product
- Discover our top product MARK2 Primary Antibody
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- 应用备注
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ELISA (1:1000-1:3000)
Western Blot (1:250-1:1000)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity." in: Current biology : CB, Vol. 14, Issue 8, pp. 736-41, (2004) (PubMed).
: "Splicing alterations in human renal allografts: detection of a new splice variant of protein kinase Par1/Emk1 whose expression is associated with an increase of inflammation in protocol biopsies of ..." in: Biochimica et biophysica acta, Vol. 1689, Issue 1, pp. 58-65, (2004) (PubMed).
: "PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling." in: Nature cell biology, Vol. 3, Issue 7, pp. 628-36, (2001) (PubMed).
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Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity." in: Current biology : CB, Vol. 14, Issue 8, pp. 736-41, (2004) (PubMed).
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- 抗原
- MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))
- 别名
- MARK2 (MARK2 产品)
- 别名
- EMK-1 antibody, EMK1 antibody, PAR-1 antibody, Par-1b antibody, Par1b antibody, AU024026 antibody, Emk antibody, Par-1 antibody, mKIAA4207 antibody, microtubule affinity regulating kinase 2 antibody, MAP/microtubule affinity regulating kinase 2 antibody, MARK2 antibody, Mark2 antibody
- 基因ID
- 2011
- 途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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