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S100A8 抗体

S100A8 适用: 人 WB 宿主: 小鼠 Monoclonal ABM4D13 unconjugated
产品编号 ABIN5027784
发货至: 中国
  • 抗原 See all S100A8 抗体
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    适用
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    宿主
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    小鼠
    克隆类型
    • 86
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    单克隆
    标记
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    This S100A8 antibody is un-conjugated
    应用范围
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    Western Blotting (WB)
    纯化方法
    Protein G Chromatography
    免疫原
    Full length recombinant S100A8 protein was used as the immunogen for this antibody.
    克隆位点
    ABM4D13
    亚型
    IgG1 kappa
    Top Product
    Discover our top product S100A8 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    S100A8 (S100 Calcium Binding Protein A8 (S100A8))
    别名
    S100A8 (S100A8 产品)
    别名
    60B8AG antibody, CAGA antibody, CFAG antibody, CGLA antibody, CP-10 antibody, L1Ag antibody, MA387 antibody, MIF antibody, MRP8 antibody, NIF antibody, P8 antibody, Mrp8 antibody, S100A8 antibody, 60B8Ag antibody, AI323541 antibody, B8Ag antibody, CFAg antibody, Caga antibody, p8 antibody, MRP-8 antibody, S100 calcium binding protein A8 antibody, S100 calcium binding protein A8 (calgranulin A) antibody, S100A8 antibody, S100a8 antibody
    背景
    S100A8 is a low molecular weight (10 kDa) secreted cytoplasmic protein belonging to S100 family of calcium- and zinc-binding protein. S100A8 regulates a number of cellular processes, such as, inflammation, antimicrobial, oxidant-scavenging and apoptosis-inducing activities, cell cycle progression and differentiation, leukocyte arachidonic acid trafficking and metabolism. S100A8 is a homodimer but predominantly remains as heterodimer with S100A9 and the S100A8/S100A9 complex is called as Calprotectin. S100A8 is generally expressed in myeloid cells, neutrophils, monocytes and keratinocytes but high levels are found in the serum sample of patients with inflammatory diseases, such as, rheumatoid, cystic fibrosis, inflammatory bowel disease, systemic lupus erythematosus, progressive systemic sclerosis and many other inflammatory diseases. S100A8 is also associated with Psoriasis (an inflammatory skin disorder characterized by keratinocyte hyperproliferation and altered differentiation).
    分子量
    10 kDa
    基因ID
    20201
    UniProt
    P27005
    途径
    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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