TNFRSF10A 抗体 (AA 2-203)
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- 抗原 See all TNFRSF10A 抗体
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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抗原表位
- AA 2-203
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF10A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Protein G Chromatography
- 免疫原
- A partial length recombinant human TRAIL/DR4 protein (amino acids 2-203) was used as an immunogen for this antibody.
- 克隆位点
- ABM1B11
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TNFRSF10A Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody
TNFRSF10A 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal DR-4-02 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 269-468) antibodyTNFRSF10A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 269-468) antibodyTNFRSF10A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody (FITC)TNFRSF10A 适用: 人 FACS 宿主: 小鼠 Monoclonal DR-4-02 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibody (PE)TNFRSF10A 适用: 人 FACS 宿主: 小鼠 Monoclonal DR-4-02 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (AA 105-204) antibodyTNFRSF10A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibodyTNFRSF10A 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibodyTNFRSF10A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (C-Term) antibodyTNFRSF10A 适用: 人 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) antibodyTNFRSF10A 适用: 人 FACS, IP, ICC, Func 宿主: 小鼠 Monoclonal DR-4-02 unconjugated
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- 应用备注
- WB: 2-4 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 0.05 % BSA, PH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- 抗原
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- 别名
- TRAIL/DR4 (TNFRSF10A 产品)
- 别名
- APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody
- 背景
- Death receptor 4 (DR4) or TRAIL-R1, a member of the tumor necrosis factor receptor superfamily, is a cell surface receptor that triggers the apoptotic machinery upon binding to its ligand tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. DR4 expression is enhanced by DNA damage whether induced by ionizing radiation or by chemotherapeutic agents. On binding DR4, TRAIL induces cell death via caspase-dependent apoptosis. DR4 mediate oligomeric Abeta induction of extrinsic apoptotic pathways in human microvascular cerebral endothelial cells with activation of both caspase-8 and caspase-9. It is considered a promising molecular target for cancer therapy.
- 分子量
- 50 kDa
- 基因ID
- 8797
- UniProt
- O00220
- 途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
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