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ACVRL1 抗体 (AA 326-503)

ACVRL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5027022
发货至: 中国
  • 抗原 See all ACVRL1 抗体
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    抗原表位
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 326-503
    适用
    • 61
    • 29
    • 17
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 55
    • 5
    • 1
    • 1
    克隆类型
    • 53
    • 8
    多克隆
    标记
    • 40
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACVRL1 antibody is un-conjugated
    应用范围
    • 51
    • 31
    • 30
    • 13
    • 11
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Protein A Chromatography
    免疫原
    A partial length recombinant ALK-1 protein (amino acids 326-503) was used as the immunogen for this antibody
    亚型
    IgG
    Top Product
    Discover our top product ACVRL1 Primary Antibody
  • 应用备注
    WB: 2-4 μg/mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.05 % BSA, PH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • 抗原
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    别名
    ALK1 (ACVRL1 产品)
    别名
    ACVRL1 antibody, vgb antibody, alk1 antibody, zehn1109 antibody, hm:zehn1109 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, R-3 antibody, R3 antibody, SETHKIR antibody, AI115505 antibody, AI427544 antibody, Acvrlk1 antibody, Alk1 antibody, activin A receptor like type 1 antibody, activin A receptor type II-like 1 antibody, activin A receptor, type II-like 1 antibody, ACVRL1 antibody, acvrl1 antibody, Acvrl1 antibody
    背景
    ALK-1 or Activin receptor-like kinase-1 is a type I cell surface receptor for the TGF-beta (transforming growth factor-beta) super family of proteins. It is expressed predominantly in endothelial cells with moderate expression in smooth muscle cells, myofibroblast, hepatic stellate cells, chondrocytes, monocytes, myoblasts, macrophages and fibroblasts. ALK-1 plays a pivotal role in vascular remodelling and angiogenesis. More specifically its key function is in arterial/venous differentiation during embryonic vascular development. Mutations in ALK-1 gene (12q11-14) causes HHT2 (Hereditary Haemorrhagic Telangiectasia type 2), an autosomal dominant multisystem vascular dysplasia caused by a haploinsufficiency mechanism.
    分子量
    56 kDa
    基因ID
    94
    UniProt
    P37023
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