ACVRL1 antibody, vgb antibody, alk1 antibody, zehn1109 antibody, hm:zehn1109 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, R-3 antibody, R3 antibody, SETHKIR antibody, AI115505 antibody, AI427544 antibody, Acvrlk1 antibody, Alk1 antibody, activin A receptor like type 1 antibody, activin A receptor type II-like 1 antibody, activin A receptor, type II-like 1 antibody, ACVRL1 antibody, acvrl1 antibody, Acvrl1 antibody
背景
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008],ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I,Amino acid metabolism,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Endocrine & Metabolism,Growth factors,Kinase,Signal Transduction,ACVRL1