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Histone 3 抗体 (H3K27me3) (AbBy Fluor® 680)

This anti-Histone 3 antibody is a 兔 多克隆 antibody detecting Histone 3 in WB 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN5004707
发货至: 中国

Quick Overview for Histone 3 抗体 (H3K27me3) (AbBy Fluor® 680) (ABIN5004707)

抗原

See all Histone 3 (H3) 抗体
Histone 3 (H3) (Histone H3 (H3))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Histone 3 antibody is conjugated to AbBy Fluor® 680

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
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    H3K27me3

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic methyl peptide derived from human Histone H3 around methylation site of Lys27

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Histone 3 (H3) (Histone H3 (H3))

    别名

    Histone H3

    背景

    Synonyms: Histone H3, H3 histone family member E pseudogene, H3F3, HIST3H3, Histone H3 3 pseudogene.

    Background: Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

    基因ID

    3020
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