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TNFRSF10A 抗体 (N-Term)

TNFRSF10A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499764
发货至: 中国
  • 抗原 See all TNFRSF10A 抗体
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    抗原表位
    • 13
    • 7
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
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    N-Term
    适用
    • 86
    • 5
    • 3
    • 1
    • 1
    宿主
    • 46
    • 40
    克隆类型
    • 48
    • 38
    多克隆
    标记
    • 47
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
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    This TNFRSF10A antibody is un-conjugated
    应用范围
    • 43
    • 31
    • 25
    • 19
    • 17
    • 11
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    DR4 antibody was raised against a peptide corresponding to amino acid 1 to 20 of human DR4 mature protein.
    纯化方法
    DEAE
    免疫原
    Human DR4 (N-Terminus) Peptide
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF10A Primary Antibody
  • 应用备注
    ELISA. Western Blot: 1/500 to 1/1000. A 57 kDa band can be detected. DR4 antibody has no crossreaction to DR5.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
    别名
    CD261 / TRAILR1 (TNFRSF10A 产品)
    别名
    APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody
    背景
    Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1. The ligand for this novel death receptor has been identified and termed TRAIL2,3, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1)4. DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kappaB activation in many tissues and cells.Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A
    基因ID
    8797
    UniProt
    O00220
    途径
    Apoptosis, Positive Regulation of Endopeptidase Activity
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