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ACVR1C/ALK7 抗体 (N-Term)

ACVR1C 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499209
发货至: 中国
  • 抗原 See all ACVR1C/ALK7 (ACVR1C) 抗体
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    抗原表位
    • 16
    • 9
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 44
    • 42
    • 28
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 53
    • 5
    克隆类型
    • 55
    • 3
    多克隆
    标记
    • 28
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACVR1C/ALK7 antibody is un-conjugated
    应用范围
    • 50
    • 25
    • 20
    • 13
    • 13
    • 11
    • 9
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to ACVR1C near the amino terminus.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    ACVR1C antibody was raised against a 15 amino acid peptide near the amino terminus of the human ACVR1C.
    亚型
    IgG
    Top Product
    Discover our top product ACVR1C Primary Antibody
  • 应用备注
    ELISA. Western Blot: ACVR1C antibody can be used for detection of ACVR1C at 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    Abstract
    ACVR1C 产品
    别名
    ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody
    背景
    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. ACVR1C, also known as ALK7, is a type I activin receptor and plays a role in cell differentiation, growth arrest and apoptosis. ACVR1C can mediate signaling by ligans such as Nodal, GDF-1/3, activin B and activin AB, all of which can also signal through the ubiquitous activin type I receptor ACVR1B (also known as ALK4). ACVR1C is a novel marker specifically expressed during the late phase of adipocyte differentiation. ACVR1C is dispensable for mouse embryogenesis, which suggests alternative functions for this receptor in postnatal development and tissue homeostasis. ACVR1C plays an important role in regulating the functional plasticity of pancreatic islets, negatively affecting beta-cell function by mediating the effects of activin B on Ca2+ signaling. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1B.Synonyms: ACTR-IC, ACTRIC, ALK7, Activin receptor-like kinase 7
    基因ID
    130399
    NCBI登录号
    NP_001104501
    UniProt
    Q8NER5
    途径
    Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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