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- 抗原 See all TR4 (NR2C2) 抗体
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Tak1 protein. (region surrounding Asp181)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product NR2C2 Primary Antibody
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anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 560-600) antibody
NR2C2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 43-152) antibodyNR2C2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 62-356) antibodyNR2C2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8F2E8 unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (pThr184), (pThr187) antibodyNR2C2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 240-380) antibodyNR2C2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 1-530) antibodyNR2C2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) antibodyNR2C2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (pSer192) antibodyNR2C2 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 410-444), (pSer439) antibodyNR2C2 适用: 人 WB, IF 宿主: 兔 Polyclonal RB56649 unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 410-444), (Ser439) antibodyNR2C2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB56649 unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- 别名
- NR2C2 (NR2C2 产品)
- 别名
- TAK1 antibody, TR2R1 antibody, TR4 antibody, hTAK1 antibody, Tr4 antibody, gb:dq017625 antibody, im:6911408 antibody, mKIAA4145 antibody, nuclear receptor subfamily 2 group C member 2 antibody, nuclear receptor subfamily 2, group C, member 2 antibody, NR2C2 antibody, Nr2c2 antibody, nr2c2 antibody
- 背景
- Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 is a 74 kDa protein with intrinsic kinase activity towards serine/threonine residues and that is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGFbeta-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGFbeta stimulation.Synonyms: Nuclear receptor subfamily 2 group C member 2, Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, TAK1, TR4, Testicular receptor 4
- 分子量
- approx. 70, 82 kDa
- 基因ID
- 7182
- NCBI登录号
- NP_003289
- UniProt
- P49116
- 途径
- TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
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