TR4 抗体 (pSer192)
(1 reference)-
- 抗原 See all TR4 (NR2C2) 抗体
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
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抗原表位
- pSer192
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human TAK1 around the phosphorylation site of Ser192
- 亚型
- IgG
- Top Product
- Discover our top product NR2C2 Primary Antibody
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anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 560-600) antibody
NR2C2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 43-152) antibodyNR2C2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2A5 unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 62-356) antibodyNR2C2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8F2E8 unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (pThr184), (pThr187) antibodyNR2C2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 240-380) antibodyNR2C2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 1-530) antibodyNR2C2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) antibodyNR2C2 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 410-444), (pSer439) antibodyNR2C2 适用: 人 WB, IF 宿主: 兔 Polyclonal RB56649 unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 410-444), (Ser439) antibodyNR2C2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB56649 unconjugated
anti-Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 400-500) antibody (HRP)NR2C2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal HRP
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "The PPARβ/δ agonist GW501516 attenuates peritonitis in peritoneal fibrosis via inhibition of TAK1-NFκB pathway in rats." in: Inflammation, Vol. 37, Issue 3, pp. 729-37, (2014) (PubMed).
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: "The PPARβ/δ agonist GW501516 attenuates peritonitis in peritoneal fibrosis via inhibition of TAK1-NFκB pathway in rats." in: Inflammation, Vol. 37, Issue 3, pp. 729-37, (2014) (PubMed).
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- 抗原
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- 别名
- TAK1 (NR2C2 产品)
- 别名
- TAK1 antibody, TR2R1 antibody, TR4 antibody, hTAK1 antibody, Tr4 antibody, gb:dq017625 antibody, im:6911408 antibody, mKIAA4145 antibody, nuclear receptor subfamily 2 group C member 2 antibody, nuclear receptor subfamily 2, group C, member 2 antibody, NR2C2 antibody, Nr2c2 antibody, nr2c2 antibody
- 背景
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Synonyms: MAP3K7phospho S192, M3K7_HUMAN, MAP3K 7, Map3k7, MEKK7, Mitogen activated protein kinase kinase kinase 7, Mitogen-activated protein kinase kinase kinase 7, Mitogen-activated protein kinase kinase kinase 7, TAK1, TGF beta activated kinase 1, TGF-beta-activated kinase 1, TGF1a, Transforming growth factor beta activated kinase 1, Transforming growth factor-beta-activated kinase 1.
Background: TAK1 (or MAP3K7) was shown to participate in regulation of transcription by transforming growth factor beta (TGF beta). TAK1 is stimulated in response to TGF beta and bone morphogenetic protein. These results suggest that TAK1 functions as a mediator in the signaling pathway of TGF beta superfamily members. TAB1 and TAB2 are TAK1 binding proteins that may function as activators of the TAK1 (TGF b activated kinase 1) MAPKKK in TGF b signal transduction. TAB1 induced TAK1 activation promoted the dissociation of active forms of IKKa and IKK b from active TAK1, whereas the IKK mutants remained to interact with active TAK1. TNF a activated endogenous TAK1, and the kinase negative TAK1 acted as a dominant negative inhibitor against TNF a induced NFkB activation. TAK1 was suggested to act as a regulatory kinase of IKKs.
- 基因ID
- 7182
- 途径
- TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
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