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FAK 抗体 (pTyr925)

Name: FAK 抗体 (pTyr925)
SKU: ABIN498837
Availability: OutOfStock

PTK2 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated

Immunohistochemistry (IHC) analyzes of p-FAK antibody in paraffin-embedded human rat hippocampal tissue. (FAK 抗体 (pTyr925))

IHC (p)

1 image

产品编号 ABIN498837

发货至: 中国

Datasheet as PDF

抗原 See all FAK (PTK2) 抗体

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
抗原表位
43

35

34

29

28

22

22

18

16

16

11

11

8

7

6

6

5

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
pTyr925
适用
351

306

232

21

21

17

16

11

8

6

6

4

3

3

2

1

1

1

1

1
人, 小鼠, 大鼠
宿主
363

17

3

2

1

1
兔
Compatible Secondaries
克隆类型
359

28
多克隆
标记
167

19

17

13

10

10

10

10

10

10

10

10

10

10

10

10

8

8

8

8

8

8

2

1
This FAK antibody is un-conjugated
应用范围
303

134

133

122

119

70

67

45

31

27

22

4

2

2
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

特异性

This antibody detects endogenous levels of FAK protein only when phosphorylated at Tyr925.

交叉反应（详细）

Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

纯化方法

Affinity chromatography

纯度

> 95 % by SDS-PAGE

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应用备注

Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1,0 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

别名

FAK1 / PTK2 (PTK2 产品)

别名

FADK antibody, FAK antibody, FAK1 antibody, FRNK antibody, PPP1R71 antibody, p125FAK antibody, pp125FAK antibody, PTK2 antibody, Fadk antibody, mKIAA4203 antibody, fak antibody, fak1a antibody, ptk2 antibody, ptk2a antibody, wu:fa18c04 antibody, zgc:66114 antibody, CG10023 antibody, CT28129 antibody, DFAK antibody, DFak antibody, DFak56 antibody, Dfak antibody, Dfak56 antibody, DmFAK antibody, Dmel\\CG10023 antibody, Fak56 antibody, Fak56D antibody, fak56 antibody, protein tyrosine kinase 2 antibody, protein tyrosine kinase 2 L homeolog antibody, PTK2 protein tyrosine kinase 2 antibody, protein tyrosine kinase 2ab antibody, Focal adhesion kinase antibody, PTK2 antibody, ptk2.L antibody, Ptk2 antibody, ptk2ab antibody, Fak antibody

背景

Focal adhesion kinase was initially identified as a major 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src-encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase whose sequence and structural organization are unique as compared to other proteins described to date. Localization of p125 by immunofluorescence suggests that it is primarily found in cellular focal adhesions leading to its designation as focal adhesion kinase (FAK). FAK is concentrated at the basal edge of only basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds, and is activated and localized to the focal adhesions of spreading keratinocytes in culture.Synonyms: FADK1, FAK, Focal adhesion kinase 1, Protein-tyrosine kinase 2, pp125FAK

分子量

approx. 125 kDa

基因ID

5747

NCBI登录号

NP_005598

UniProt

Q05397

途径

Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling