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FAK 抗体 (AA 700-800)

PTK2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6146423
发货至: 中国
  • 抗原 See all FAK (PTK2) 抗体
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    抗原表位
    • 37
    • 29
    • 27
    • 25
    • 23
    • 23
    • 18
    • 18
    • 16
    • 16
    • 13
    • 11
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 700-800
    适用
    • 325
    • 285
    • 220
    • 22
    • 21
    • 18
    • 17
    • 12
    • 9
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 337
    • 18
    • 3
    • 2
    • 1
    • 1
    克隆类型
    • 327
    • 35
    多克隆
    标记
    • 178
    • 19
    • 16
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 1
    This FAK antibody is un-conjugated
    应用范围
    • 298
    • 126
    • 122
    • 121
    • 108
    • 75
    • 67
    • 51
    • 31
    • 29
    • 25
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    序列
    TVSWDSGGSD EAPPKPSRPG YPSPRSSEGF YPSPQHMVQT NHYQVSGYPG SHGITAMAGS IYPGQASLLD QTDSWNHRPQ EIAMWQPNVE DSTVLDLRGI G
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FAK (NP_722560.1).
    亚型
    IgG
    Top Product
    Discover our top product PTK2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Shen, Sun, Sun, Li, Wu, Li, Chen, Liu, Cui, Zhou: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." in: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).

  • 抗原
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    别名
    PTK2 (PTK2 产品)
    别名
    FADK antibody, FAK antibody, FAK1 antibody, FRNK antibody, PPP1R71 antibody, p125FAK antibody, pp125FAK antibody, PTK2 antibody, Fadk antibody, mKIAA4203 antibody, fak antibody, fak1a antibody, ptk2 antibody, ptk2a antibody, wu:fa18c04 antibody, zgc:66114 antibody, CG10023 antibody, CT28129 antibody, DFAK antibody, DFak antibody, DFak56 antibody, Dfak antibody, Dfak56 antibody, DmFAK antibody, Dmel\\CG10023 antibody, Fak56 antibody, Fak56D antibody, fak56 antibody, protein tyrosine kinase 2 antibody, protein tyrosine kinase 2 L homeolog antibody, PTK2 protein tyrosine kinase 2 antibody, protein tyrosine kinase 2ab antibody, Focal adhesion kinase antibody, PTK2 antibody, ptk2.L antibody, Ptk2 antibody, ptk2ab antibody, Fak antibody
    背景
    This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.,FADK,FAK,FAK1,FRNK,PPP1R71,p125FAK,pp125FAK,PTK2,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Actins,Extracellular Matrix,Immunology & Inflammation,Cardiovascular,Angiogenesis,PTK2
    分子量
    39 kDa/48 kDa/63 kDa/99 kDa/114 kDa/119 kDa/120 kDa
    基因ID
    5747
    UniProt
    Q05397
    途径
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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