Stathmin 1 抗体 (pSer25)
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- 抗原 See all Stathmin 1 (STMN1) 抗体
- Stathmin 1 (STMN1)
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抗原表位
- pSer25
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Stathmin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Op18 protein only when phosphorylated at Ser25.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product STMN1 Primary Antibody
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anti-Stathmin 1 (STMN1) (AA 2-149) antibody
STMN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Stathmin 1 (STMN1) antibodySTMN1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Stathmin 1 (STMN1) (C-Term) antibodyKO Validated STMN1 适用: 人 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Stathmin 1 (STMN1) (pSer38) antibodySTMN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stathmin 1 (STMN1) (pSer25) antibodySTMN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stathmin 1 (STMN1) (pSer15) antibodySTMN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stathmin 1 (STMN1) (C-Term) antibodyVerified STMN1 适用: 人, 小鼠 WB, IHC, ELISA, EIA 宿主: 山羊 Polyclonal unconjugated
anti-Stathmin 1 (STMN1) (AA 13-78) antibodySTMN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Stathmin 1 (STMN1) (N-Term) antibodySTMN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Stathmin 1 (STMN1) (pSer16) antibodySTMN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS, pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Stathmin 1 (STMN1)
- 别名
- Stathmin / STMN1 (STMN1 产品)
- 别名
- C1orf215 antibody, LAP18 antibody, Lag antibody, OP18 antibody, PP17 antibody, PP19 antibody, PR22 antibody, SMN antibody, 19k antibody, Lap18 antibody, Op18 antibody, P18 antibody, P19 antibody, Pig antibody, Pp17 antibody, Pp18 antibody, Pp19 antibody, Pr22 antibody, Smn antibody, prosolin antibody, op18 antibody, stathmin antibody, stmn1 antibody, stmn1a antibody, lag antibody, lap18 antibody, pp17 antibody, pp19 antibody, pr22 antibody, smn antibody, fj43c10 antibody, wu:fj38b07 antibody, wu:fj43c10 antibody, zgc:110159 antibody, cb959 antibody, wu:fb14e04 antibody, zgc:136942 antibody, stmn1-a antibody, stmn1b antibody, xo35 antibody, stathmin 1 antibody, stathmin 1 S homeolog antibody, stathmin 1b antibody, stathmin 1a antibody, stathmin-like antibody, stathmin antibody, stathmin 1 L homeolog antibody, STMN1 antibody, Stmn1 antibody, stmn1.S antibody, stmn1 antibody, stmn1b antibody, stmn1a antibody, LOC100229194 antibody, stmn1.L antibody
- 背景
- Oncoprotein 18 (Op18) is a regulator of microtubule (MT) dynamics. Op18 is a target for both cell cycle and cell surface receptor-coupled kinase systems, and phosphorylation of Op18 on specific combinations of amino acid residues has been shown to switch off MT-destabilizing activity of Op18. Induced expression of the catalytic subunit of cAMPdependent protein kinase (PKA) results in a dramatic increase in cellular MT polymer content concomitant with phosphorylation and partial degradation of Op18. Phosphorylation of Op18 on two specific sites, Serine 16 and Serine 63, is necessary and sufficient for PKA to switch off Op18 activity in intact cells. PKA phosphorylation down-regulates the MT-destabilizing activity of Op18, which in turn promotes increased Tubulin polymerization. Op18 has the potential to regulate the MT system in response to external signals such as cAMP-linked agonists.Synonyms: LAP18, Leukemia-associated phosphoprotein p18, Metablastin, OP18, Oncoprotein 18, Op18, Phosphoprotein p19, Prosolin, Protein Pr22, pp17, pp19
- 分子量
- approx. 19 kDa
- 基因ID
- 3925
- NCBI登录号
- NP_005554
- UniProt
- P16949
- 途径
- MAPK Pathway, Microtubule Dynamics
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