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- 抗原 See all Translin (TSN) 抗体
- Translin (TSN)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Translin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This Antibody detects endogenous levels of Translin protein. (region surrounding Glu121)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product TSN Primary Antibody
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anti-Translin (TSN) (AA 50-150) antibody
TSN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Translin (TSN) (Internal Region) antibodyTSN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Translin (TSN) (AA 115-197) antibodyTSN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Translin (TSN) (AA 109-138) antibodyTSN 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB31284 unconjugated
anti-Translin (TSN) (C-Term) antibodyTSN 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Translin (TSN) (AA 113-162) antibodyTSN 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Hamster, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Translin (TSN) (Center) antibodyTSN 适用: 人, 小鼠, 大鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Translin (TSN) (AA 101-150) antibodyTSN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Translin (TSN) (Internal Region) antibodyTSN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Translin (TSN) (AA 116-146), (Middle Region) antibodyTSN 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Translin (TSN)
- Abstract
- TSN 产品
- 别名
- tsn antibody, MGC52533 antibody, TSN antibody, CG11761 antibody, Dmel\\CG11761 antibody, TB-RBP antibody, BCLF-1 antibody, C3PO antibody, RCHF1 antibody, REHF-1 antibody, TBRBP antibody, TRSLN antibody, 2610034C24Rik antibody, AU040286 antibody, translin L homeolog antibody, translin antibody, haloacid dehalogenase antibody, Translin antibody, tsn.L antibody, TSN antibody, trsn antibody, MMAH_RS03470 antibody, TAGG_RS05275 antibody, Igag_0962 antibody, MFER_RS03645 antibody, DESMU_RS01315 antibody, ARCVE_RS05265 antibody, MZHIL_RS01310 antibody, Tsn antibody
- 背景
- Translin, also designated testis brain RNA-binding protein (TB-RBP), is a single-stranded DNA- and RNA-binding protein that binds to the 3' UTR regions (Y and H elements) of stored mRNAs, which suppresses their in vitro translation. The human translin gene maps to chromosome 2q21.1 and encodes a 26 kDa protein that has been highly conserved throughout evolution. Translin forms a ring-shaped structure, which is responsible for DNA binding, and also contains a leucine zipper motif, which is thought to enable translin to form dimers. Translin exports specific mRNAs out of the nucleus, supported by its localization in both the nuclei and cytoplasm of neurons, and regulates their translation. Association with Trax (translin-associated factor X), inhibits the binding of translin to RNA, but enhances its binding to single stranded DNA sequences. Breakpoints in the TLS/FUS and CHOP loci contain consensus recognition motifs of translin, which associates with chromosomal translocations in liposarcomas.
- 分子量
- approx. 26 kDa
- 基因ID
- 7247
- NCBI登录号
- NP_004613
- UniProt
- Q15631
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