Translin 抗体 (AA 101-150)
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北京 101111
Quick Overview for Translin 抗体 (AA 101-150) (ABIN1533915)
抗原
See all Translin (TSN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-150
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原理
- Translin Antibody
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特异性
- Translin Polyclonal Antibody detects endogenous levels of Translin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TSN. AA range:101-150
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Translin (TSN)
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别名
- TSN
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背景
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Synonyms: TSN, Translin, Component 3 of promoter of RISC, C3PO
Background: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012],
Gene Name: TSN
Protein Name: Translin
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分子量
- 26 kDa
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基因ID
- 7247
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OMIM
- 600575
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UniProt
- Q15631
抗原
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