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CPT2 抗体 (Internal Region)

CPT2 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN498063
发货至: 中国
  • 抗原 See all CPT2 抗体
    CPT2 (Carnitine Palmitoyltransferase 2 (CPT2))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 141-154, Internal Region
    适用
    • 63
    • 33
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, Pig, 犬
    宿主
    • 58
    • 5
    • 2
    山羊
    克隆类型
    • 53
    • 12
    多克隆
    标记
    • 32
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CPT2 antibody is un-conjugated
    应用范围
    • 44
    • 34
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-PKSEYNDQLT RATN
    特异性
    Recognizes Carnitine O-palmitoyltransferase CPT2
    交叉反应 (详细)
    Species reactivity (expected):Rat, Canine (Dog), Bovine, Pig.
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide from the internal region of Human CPT2 according to NP_000089.1. Genename: CPT2
    Top Product
    Discover our top product CPT2 Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit: 1/8000. Western blot: 1-3 μg/mL. Detects a band of Approx 70 kDa in Human and Mouse Liver lysates. An additional band of unknown identity was also consistently observed at 20 kDa. Thisband was successfully blocked by incubation with the immunizing peptide.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CPT2 (Carnitine Palmitoyltransferase 2 (CPT2))
    别名
    CPT2 (CPT2 产品)
    别名
    CPT1 antibody, CPTASE antibody, IIAE4 antibody, AI323697 antibody, CPTII antibody, cg2107 antibody, wu:fa03e08 antibody, wu:fb54a02 antibody, zgc:101627 antibody, carnitine palmitoyltransferase 2 antibody, carnitine O-palmitoyltransferase 2, mitochondrial antibody, carnitine palmitoyltransferase 2 S homeolog antibody, CPT2 antibody, LOC100214547 antibody, Cpt2 antibody, cpt2.S antibody, cpt2 antibody
    背景
    Carnitine palmitoyltransferase II (CPT2) together with carnitine palmitoyltransferase I oxidizes long-chain fatty acids in the mitochondria. Defects in CPT2 are the cause of carnitine palmitoyltransferase 2 deficiency (CPT2D) also known as CPT-II deficiency or CPT2 deficiency. CPT2D is an autosomal recessive disorder characterized by recurrent myoglobinuria, episodes of muscle pain, stiffness, and rhabdomyolysis. These symptoms are triggered by prolonged exercise, fasting or viral infection and patients are usually young adults. In addition to this classical, late-onset, muscular type, a hepatic or hepatocardiomuscular form has been reported in infants. Clinical pictures in these children or neonates include hypoketotic hypoglycemia, liver dysfunction, cardiomyopathy and sudden death.Synonyms: CPT II, Carnitine O-palmitoyltransferase 2, Carnitine palmitoyltransferase II, mitochondrial
    基因ID
    1376
    NCBI登录号
    NP_000089
    UniProt
    P23786
    途径
    Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process
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