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NPC2 抗体 (Internal Region)

NPC2 适用: 人 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN498021
发货至: 中国
  • 抗原 See all NPC2 抗体
    NPC2 (Niemann-Pick Disease, Type C2 (NPC2))
    抗原表位
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 34
    • 22
    • 16
    • 5
    宿主
    • 36
    • 5
    • 2
    山羊
    克隆类型
    • 40
    • 3
    多克隆
    标记
    • 20
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPC2 antibody is un-conjugated
    应用范围
    • 31
    • 17
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    QAEPVQFKDC GSVD
    特异性
    Recognizes Niemann-Pick disease type C2 NPC2.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_006423.1. Genename: NPC2
    Top Product
    Discover our top product NPC2 Primary Antibody
  • 应用备注
    Peptide ELISA: Limit Dilution: 1/2000. Western blot: 0.3-1 μg/mL. Experiments gave bands at approx 20 kDa and 20 kDa in HumanTestis lysates. These bands correspond to earlier findings in literature with differentantibodies (Ref.2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NPC2 (Niemann-Pick Disease, Type C2 (NPC2))
    别名
    NPC2 (NPC2 产品)
    别名
    2700012J19Rik antibody, AA408070 antibody, AU045843 antibody, HE1 antibody, EDDM1 antibody, re1 antibody, CE1 antibody, EPI-1 antibody, cb292 antibody, sb:cb292 antibody, NPC intracellular cholesterol transporter 2 antibody, Niemann-Pick disease, type C2 antibody, Npc2 antibody, NPC2 antibody, npc2 antibody
    背景
    Niemann-Pick C2 (NPC2) is a 22 kDa soluble lysosomal glycoprotein important for cholesterol and sphingolipid transport in the lysosome. This protein was initially identified as the second Niemann-Pick type C (NPC) gene based on its ability to bind the mannose-6 phosphate receptor. NPC disease is an autosomal recessively inherited neurodegenerative lysosomal storage disease and its associated with abnormal cholesterol accumulation in cells. Mutations in the NPC2 gene cause 5 % of the cases, the rest and majority being caused by NPC1 mutations.Synonyms: Epididymal secretory protein E1
    基因ID
    10577
    NCBI登录号
    NP_006423
    UniProt
    P61916
    途径
    SARS-CoV-2 Protein Interactome
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