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NPC2 抗体 (AA 20-80)

NPC2 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385817
发货至: 中国
  • 抗原 See all NPC2 抗体
    NPC2 (Niemann-Pick Disease, Type C2 (NPC2))
    抗原表位
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 20-80
    适用
    • 46
    • 33
    • 22
    • 5
    小鼠
    宿主
    • 47
    • 5
    • 2
    克隆类型
    • 51
    • 3
    多克隆
    标记
    • 19
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPC2 antibody is un-conjugated
    应用范围
    • 30
    • 16
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Sheep
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Niemann Pick C2
    亚型
    IgG
    Top Product
    Discover our top product NPC2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    NPC2 (Niemann-Pick Disease, Type C2 (NPC2))
    别名
    NPC2/Niemann Pick C2 (NPC2 产品)
    别名
    2700012J19Rik antibody, AA408070 antibody, AU045843 antibody, HE1 antibody, EDDM1 antibody, re1 antibody, CE1 antibody, EPI-1 antibody, cb292 antibody, sb:cb292 antibody, NPC intracellular cholesterol transporter 2 antibody, Niemann-Pick disease, type C2 antibody, Npc2 antibody, NPC2 antibody, npc2 antibody
    背景

    Synonyms: EDDM1, Epididymal protein 1, Epididymal secretory protein, Epididymal secretory protein E1, HE1, Human epididymis-specic protein 1, Niemann-Pick disease type C2, Niemann-Pick disease type C2 protein, NPC2, NPC2_HUMAN, Tissue specic secretory protein.

    Background: NPC2 is a secreted protein mapping against gene 14q24.3 (1,2). NPC2 regulates the lipid composition of sperm membranes during maturation in the epididymis(1,2). Mutations in the NPC2 gene may cause Nieman-Pick type C2 disease and frontal lobe atrophy (1,2,3). Nieman-Pick type C2 is a fatal hereditary disease characterized by defective lysosome release of cholesterol (3). The disease is caused by HE1 deficiency, a lysosmal protein proven to be undetectable in fibroblasts from NPC2 patients (3). This differentiates NPC2 from NPC1, as NPC1 has HE1 protein present (3).

    途径
    SARS-CoV-2 Protein Interactome
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