MCM2 抗体 (AA 649-677)
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Quick Overview for MCM2 抗体 (AA 649-677) (ABIN3031801)
抗原
See all MCM2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 649-677
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交叉反应 (详细)
- Expected species reactivity: Xenopus
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 649-677 from the human protein was used as the immunogen for this MCM2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MCM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-2000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MCM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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别名
- MCM2
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背景
- MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
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UniProt
- P49736
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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