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LATS2 抗体 (AA 228-258)

LATS2 适用: 小鼠, 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031595
发货至: 中国
  • 抗原 See all LATS2 抗体
    LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
    抗原表位
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 228-258
    适用
    • 63
    • 55
    • 15
    • 4
    小鼠, 人
    宿主
    • 71
    • 2
    克隆类型
    • 71
    • 2
    多克隆
    标记
    • 20
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    This LATS2 antibody is un-conjugated
    应用范围
    • 31
    • 30
    • 12
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Purified
    免疫原
    A portion of amino acids 228-258 from the human protein was used as the immunogen for this LATS2 antibody.
    亚型
    Ig Fraction
    Top Product
    Discover our top product LATS2 Primary Antibody
  • 应用备注
    Titration of the LATS2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    In 1X PBS pH 7.4 with 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot the LATS2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原
    LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
    别名
    LATS2 (LATS2 产品)
    别名
    4932411G09Rik antibody, AV277261 antibody, AW228608 antibody, KPM antibody, lats2 antibody, large tumor suppressor kinase 2 antibody, large tumor suppressor 2 antibody, LATS2 antibody, Lats2 antibody, lats2 antibody
    背景
    LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
    UniProt
    Q9NRM7
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